s100a8
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  • Official Full Name
  • S100 calcium binding protein A8
  • Background
  • The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]
  • Synonyms
  • S100A8; S100 calcium binding protein A8; P8; MIF; NIF; CAGA; CFAG; CGLA; L1Ag; MRP8; CP-10; MA387; 60B8AG; protein S100-A8; MRP-8; calgranulin A; calgranulin-A; cystic fibrosis antigen; calprotectin L1L subunit; urinary stone protein band A; leukocyte L1 complex light chain; migration inhibitory factor-related protein 8; S100 calcium-binding protein A8 (calgranulin A);
Cat.#:S100A8-1013HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Calprotectin Protein
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Cat.#:S100A8-320HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human S100A8 Protein (Met 1 - Glu 93)
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Cat.#:S100A8-226HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human S100A8 Protein, MYC/DDK-tagged
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Cat.#:S100A8-294HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human S100A8 Protein, MYC/DDK-tagged
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Cat.#:S100a8-1361RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat S100a8 Protein, His-tagged
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Cat.#:S100A8 & S100A9-2217HTag:His/Flag
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human S100A8 & S100A9 Heterodimer Protein, His & Flag tagged
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Cat.#:S100A8-2216HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human S100A8, His tagged
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Cat.#:S100A8-2492HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A8, GST-tagged
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Cat.#:S100A8-3732HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A8, His-tagged
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Cat.#:S100A8-432HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A8 protein
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Cat.#:S100A8-14622MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse S100A8 Protein
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Cat.#:S100a8-3545MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100a8, His-tagged
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Cat.#:S100a8-405MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100a8, His tagged
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Cat.#:S100a8-1803RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat S100a8 protein, His & T7-tagged
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Cat.#:S100A8-5215RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat S100A8 Protein
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Cat.#:S100A8-4064RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey S100A8 Protein, His-tagged
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Cat.#:S100A8-1804RTag:His/T7
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit S100A8 protein, His & T7-tagged
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Cat.#:S100A8-1801CTag:His/S
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle S100A8 protein, His & S-tagged
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Cat.#:S100A8-1802PTag:His/T7
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig S100A8 protein, His & T7-tagged
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Cat.#:S100a8-5107MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100 Calcium Binding Protein A8 (calgranulin A), His-tagged
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Cat.#:S100A8-685HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human S100A8 cell lysate
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Protein Function

S100A8 has several biochemical functions, for example, RAGE receptor binding, Toll-like receptor 4 binding, arachidonic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A8 itself. We selected most functions S100A8 had, and list some proteins which have the same functions with S100A8. You can find most of the proteins on our site.
Function
Related Protein
Function RAGE receptor binding
Related Protein HMGB1; S100A9; S100A8; S100A13; HMGB2; FPR1; S100A4; S100A12; S100P; S100B
Function Toll-like receptor 4 binding
Related Protein S100A8; TIRAP; S100A9; SAA3
Function arachidonic acid binding
Related Protein PPARG; STX3; CYP4A14; S100A8; ALOX5AP; CYP4F14; S100A9
Function calcium ion binding
Related Protein PLA2G1B; RAB11FIP4; CABP2A; CELSR2; TNNC2; EHD1; RHOT1; PLCD3A; PLS3; NCS1A
Function microtubule binding
Related Protein WHAMM; KIF7; TXNDC3; KCNH2A; EML2; CLASP1; DPYSL5; KIF9; RAE1; PRC1
Function protein binding
Related Protein CACNA2D1A; KANK2; PAWR; VBP1; MBNL1; ARAP3; CBX8; SELL; RTN4RL1; ZC3HAV1
Function zinc ion binding
Related Protein PRICKLE1A; RC3H1; LPP; ADAM20; QPCTLA; MMP3; MYT1LA; CYLD; ADA; LMO2

Interacting Protein

S100A8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A8 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A8.
S100A9; GAPDH; ESR1; NOS2; PPP2R2B

S100A8 Related Articles

Leal, RF; Planell, N; et al. Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNF alpha therapy. GUT 64:233-242(2015).
Obry, A; Lequerre, T; et al. Identification of S100A9 as Biomarker of Responsiveness to the Methotrexate/Etanercept Combination in Rheumatoid Arthritis Using a Proteomic Approach. PLOS ONE 9:-(2014).