||Ephrin-B1 (EFNB1) is a glycoprotein that is expressed on neuroepithelial cells and post-synaptically on dendritic spines in the cortex, supporting a role in synaptic plasticity in this region. Ephrin-B1 is also highly expressed on developing peripheral nerve fibers including auditory and vestibular (statoacoustic) and dorsal root ganglion nerve fibers and provides guidance signals to these cells. Ephrin-B1 participates in cell-cell repulsive and attractive signaling together with its Eph receptor. Tyrosine phosphorylation of ephrin-B1 promotes invasion of cancer cells in vivo and is a potential therapeutic target in some types of gastrointestinal cancers.
||The predicted molecular weight of Recombinant Mouse Ephrin-B1 is Mr 49.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 60 kDa.
|State Of Matter:
||>95% by SDS Page and analyzed by silver stain.
||<1.0 EU/µg as determined by the LAL method.
|Storage And Stability:
||This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.