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Recombinant Mouse Ephrin B1

Cat. No.: Efnb1-1733M
Description: Ephrin-B1 (EFNB1) is a glycoprotein that is expressed on neuroepithelial cells and post-synaptically on dendritic spines in the cortex, supporting a role in synaptic plasticity in this region. Ephrin-B1 is also highly expressed on developing peripheral nerve fibers including auditory and vestibular (statoacoustic) and dorsal root ganglion nerve fibers and provides guidance signals to these cells. Ephrin-B1 participates in cell-cell repulsive and attractive signaling together with its Eph receptor. Tyrosine phosphorylation of ephrin-B1 promotes invasion of cancer cells in vivo and is a potential therapeutic target in some types of gastrointestinal cancers.
Molecular Weight: The predicted molecular weight of Recombinant Mouse Ephrin-B1 is Mr 49.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 60 kDa.
Source: NSO Cells.
State Of Matter: Lyophilized.
Purity: >95% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: Efnb1 ephrin B1 [ Mus musculus ]
Synonyms: Efnb1; ephrin B1; Epl2; EFL-3; Elk-L; Eplg2; Lerk2; Stra1; Cek5-L; LERK-2; Cek ligand; Cek5 ligand; OTTMUSP00000019590
Gene ID: 13641
mRNA Refseq: NM_010110
Protein Refseq: NP_034240
UniProt ID: P52795
Chromosome Location: X D; X 37.0 cM
Pathway: Axon guidance
Function: ephrin receptor binding; protein binding

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