| Species : |
Mouse |
| Source : |
Mammalian Cells |
| Tag : |
Non |
| Description : |
Ephrin-B1 (EFNB1) is a glycoprotein that is expressed on neuroepithelial cells and post-synaptically on dendritic spines in the cortex, supporting a role in synaptic plasticity in this region. Ephrin-B1 is also highly expressed on developing peripheral nerve fibers including auditory and vestibular (statoacoustic) and dorsal root ganglion nerve fibers and provides guidance signals to these cells. Ephrin-B1 participates in cell-cell repulsive and attractive signaling together with its Eph receptor. Tyrosine phosphorylation of ephrin-B1 promotes invasion of cancer cells in vivo and is a potential therapeutic target in some types of gastrointestinal cancers. |
| Molecular Weight : |
The predicted molecular weight of Recombinant Mouse Ephrin-B1 is Mr 49.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 60 kDa. |
| State Of Matter : |
Lyophilized. |
| Purity : |
>95% by SDS Page and analyzed by silver stain. |
| Endotoxin : |
<1.0 EU/µg as determined by the LAL method. |
| Storage And Stability : |
This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
