Recombinant Mouse Ephrin B1

• Cat.No.: Efnb1-1733M

Specification

• Cat. No.: Efnb1-1733M
• Description: Ephrin-B1 (EFNB1) is a glycoprotein that is expressed on neuroepithelial cells and post-synaptically on dendritic spines in the cortex, supporting a role in synaptic plasticity in this region. Ephrin-B1 is also highly expressed on developing peripheral nerve fibers including auditory and vestibular (statoacoustic) and dorsal root ganglion nerve fibers and provides guidance signals to these cells. Ephrin-B1 participates in cell-cell repulsive and attractive signaling together with its Eph receptor. Tyrosine phosphorylation of ephrin-B1 promotes invasion of cancer cells in vivo and is a potential therapeutic target in some types of gastrointestinal cancers.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse Ephrin-B1 is Mr 49.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 60 kDa.
• Source: Mammalian cells
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Efnb1 ephrin B1 [ Mus musculus ]
• Synonyms: Efnb1; ephrin B1; Epl2; EFL-3; Elk-L; Eplg2; Lerk2; Stra1; Cek5-L; LERK-2; Cek ligand; Cek5 ligand; OTTMUSP00000019590
• Gene ID: 13641
• mRNA Refseq: NM_010110
• Protein Refseq: NP_034240
• UniProt ID: P52795
• Chromosome Location: X D; X 37.0 cM
• Pathway: Axon guidance
• Function: ephrin receptor binding; protein binding