Recombinant Human Fibroblast Growth Factor 9 (Glia-activating Factor)

• Cat.No.: FGF9-336H

Specification

• Cat. No.: FGF9-336H
• Description: Fibroblast growth factor 9 (glia-activating factor), also known as FGF9 is a glycosylated neurotrophic polypeptide highly expressed in brain. It is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development.
• Source: Sf21 Insect Cells.
• Molecular Weight: The predicted molecular weight of Recombinant Human FGF-9 is Mr 23 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 25-27 kDa.
• State Of Matter: Lyophilized.
• Purity: >97% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Biological Activity: The biological activity of Human FGF-9 was determined by its ability to stimulate proliferation of a mouse fibroblast cell line, Balb/3T3.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer.

Gene Information

• Gene Name: FGF9 fibroblast growth factor 9 (glia-activating factor) [ Homo sapiens ]
• Synonyms: FGF9; fibroblast growth factor 9 (glia-activating factor); GAF; SYNS3; HBFG-9; MGC119914; MGC119915; fibroblast growth factor 9; glia-activating factor; FGF-9; HBGF-9; MGC119914; OTTHUMP00000018804
• Gene ID: 2254
• mRNA Refseq: NM_002010
• Protein Refseq: NP_002001
• MIM: 600921
• UniProt ID: P31371
• Chromosome Location: 13q11-q12
• Pathway: MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton; Signaling by FGFR
• Function: fibroblast growth factor receptor binding; growth factor activity; heparin binding