"POLG" Related Products


Recombinent Human POLG protein

Cat.No.: POLG-1525H
Product Overview: Recombinant full length human DNA polymerase gamma catalytic subunit.
Description: This is the POLG gene product, the catalytic subunit of DNA polymerase gamma. Pol gamma is the mitochondrial replication and repair DNA polymerase. Defects in the POLG gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Pol gamma is also a target of various nucleotide derivatives.
Source: E. coli
Species: Human
Form: 20 mM
Tris-HCl, (pH7.5), 200 mM NaCl, 1 mM β-
mercaptoethanol, and 10% glycerol
Molecular Mass: 140 kDa
Storage: Stable for 2 years at -70 centigrade from date of
shipment. Aliquot to avoid repeated
freezing and thawing.
Gene Name: POLG polymerase (DNA directed), gamma [ Homo sapiens ]
Official Symbol: POLG
Synonyms: POLG; polymerase (DNA directed), gamma; DNA polymerase subunit gamma-1; POLG1; POLGA; PolG-alpha; PolG, catalytic subunit; mitochondrial DNA polymerase catalytic subunit; PEO; MDP1; SCAE; MIRAS; SANDO; MTDPS4A; MTDPS4B; FLJ27114;
Gene ID: 5428
mRNA Refseq: NM_001126131
Protein Refseq: NP_001119603
MIM: 174763
UniProt ID: P54098

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