fgf7
Share
  • Official Full Name
  • Fibroblast growth factor 7
  • Background
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
  • Synonyms
  • FGF7; fibroblast growth factor 7; KGF; HBGF-7; keratinocyte growth factor; OTTHUMP00000162252; heparin-binding growth factor 7; HBGF 7; HBGF7; FGF 7; FGF-7; Heparin binding growth factor 7
Cat.#:FGF7-4116HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FGF7 Protein, GST-tagged
+Inquiry
Cat.#:FGF7-5416HTag:N/A
Source (Host):HEK 293 cellsSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 7
+Inquiry
Cat.#:FGF7-594HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human Fibroblast Growth Factor 7, His-tagged
+Inquiry
Cat.#:FGF7-188HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF7 protein
+Inquiry
Cat.#:FGF7-189HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF7 protein, His/S-tagged
+Inquiry
Cat.#:FGF7-218HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human FGF7, StrepII-tagged
+Inquiry
Cat.#:FGF7-282HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF7, His-tagged
+Inquiry
Cat.#:FGF7-28410THTag:His
Source (Host):Species:Human
Product nameRecombinant Human FGF7, His-tagged
+Inquiry
Cat.#:FGF7-28647THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF7
+Inquiry
Cat.#:FGF7-512HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human FGF7
+Inquiry
Cat.#:Fgf7-190MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf7 protein, His/S-tagged
+Inquiry
Cat.#:Fgf7-500MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf7, His-tagged
+Inquiry
Cat.#:FGF7-5856MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FGF7 Protein
+Inquiry
Cat.#:Fgf7-597MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf7
+Inquiry
Cat.#:Fgf7-191RTag:His/S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fgf7 protein, His/S-tagged
+Inquiry
Cat.#:FGF7-2335RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FGF7 Protein
+Inquiry
Cat.#:Fgf7-372RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fibroblast Growth Factor 7
+Inquiry
Cat.#:FGF7-1701RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FGF7 Protein, His-tagged
+Inquiry
Cat.#:FGF7-1900CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FGF7
+Inquiry
Cat.#:FGF7-1837ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FGF7
+Inquiry
Cat.#:FGF7-682HTag:His
Source (Host):Hordeum vulgare (barley grain)Species:Human
Product nameRecombinant Human Fibroblast Growth Factor 7, His-tagged
+Inquiry
Cat.#:Fgf7-649MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fibroblast Growth Factor 7
+Inquiry
Cat.#:FGF7-6236HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FGF7 293 Cell Lysate
+Inquiry
Cat.#:FGF7-142HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human FGF7 Protein
+Inquiry
Cat.#:FGF7-14HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF-7 Reference standard
+Inquiry
Cat.#:FGF7-15HTag:
Source (Host):E. coliSpecies:Human
Product nameHuman FGF-7 Reference standard
+Inquiry
Cat.#:FGF7-P013HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF7 therapeutic protein
+Inquiry

Involved Pathway

FGF7 involved in several pathways and played different roles in them. We selected most pathways FGF7 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
PRKACAA; Fgf15; RAP1A; CACNA1BA; FGF6; FGFR2; FGF20B; SOS1; MAPK6; RAC1A
Ras signaling pathway
FGF19; BAD; NRAS; INS; PRKACG; CALM2; PLA2G12A; FGF3; ANGPT2; GNG12
Rap signaling pathway
MAPK3; RAPGEF6; ACTB; MLLT4; GNAQ; GNAI1; ARAP3; ITGAM; GRIN2B; PRKCI
PIK-Akt signaling pathway
HSP90AB1; CRTC2; RPTOR; FLT1; PKN1; IL2RB; PKN3; THBS3; SOS1; FGF16
Regulation of actin cytoskeleton
ROCK2B; SLC9A1; ARPC5L; PAK2; FGF10A; Pdgfa&Pdgfb; PIP5K1BA; FGF20B; PIK3R2; FGF8
Pathways in cancer
GLI3; MAP2K2; HGF; GNG5; WNT3; BCL2; WNT7B; CBL; FGF11; ITGA2B
Melanoma
FGF12; HGF; PDGFD; MAPK3; BAD; FGFR1; PIK3R5; FGF13; FGF19; FGF18

Protein Function

FGF7 has several biochemical functions, for example, chemoattractant activity, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF7 itself. We selected most functions FGF7 had, and list some proteins which have the same functions with FGF7. You can find most of the proteins on our site.
Function
Related Protein
Function chemoattractant activity
Related Protein CCL5; CCL3; CCL16; HMGB2; SCG2; CCL15; CXCL12; SAA4; HMGB1; CXCL12A
Function growth factor activity
Related Protein TIMP1; FGF12B; CSF2; PROK1; FGF16; INHBC; FGF1; RABEP2; FGF10; HDGF
Function heparin binding
Related Protein CCL8; REG4; BMP4; PGF; GPNMB; COL20A1; FMODA; NELL2; VEGFB; WISP1
Function protein binding
Related Protein OTOF; EED; DBNL; PPP4R4; FAM3C; UBR2; NDUFA4; TOMM7; KCNJ15; MELK
Function type 2 fibroblast growth factor receptor binding
Related Protein FGF8; FGF17; FGF18; FGF7; FGF10

Interacting Protein

FGF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF7.
FGFR2; UBQLN1; FGF1; DESI1

FGF7 Related Articles

Sheen, YS; Fan, SMY; et al. Visible Red Light Enhances Physiological Anagen Entry In Vivo and has Direct and Indirect Stimulative Effects In Vitro. LASERS IN SURGERY AND MEDICINE 47:50-59(2015).
Kook, SH; Jeon, YM; et al. Periodontal Fibroblasts Modulate Proliferation and Osteogenic Differentiation of Embryonic Stem Cells Through Production of Fibroblast Growth Factors. JOURNAL OF PERIODONTOLOGY 85:645-654(2014).