il33
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  • Official Full Name
  • interleukin 33
  • Background
  • IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011]
  • Synonyms
  • IL33; interleukin 33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules;
Cat.#:IL33-5188HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human IL33 Protein, GST-tagged
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Cat.#:IL33-1917MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse IL33 Protein
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Cat.#:Il33-5186MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il33 Protein
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Cat.#:IL33-320HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 33
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Cat.#:Il33-207MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Murine Interleukin 33
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Cat.#:Il33-286RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Interleukin 33
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Cat.#:IL33-121HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Interleukin 33, MIgG2a Fc-tagged
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Cat.#:IL33-122HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Interleukin 33, HIgG1 Fc-tagged, mutant
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Cat.#:IL33-124HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Interleukin 33, HIgG1 Fc-tagged
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Cat.#:IL33-138HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL33 protein
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Cat.#:IL33-215HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL33 protein
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Cat.#:IL33-29791THTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL33 protein, FLAG-tagged
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Cat.#:IL33-32HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL33 protein, His-tagged
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Cat.#:IL33-59HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL33, His-tagged
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Cat.#:IL33-120MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Interleukin 33, MIgG2a Fc-tagged, mutant
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Cat.#:IL33-130MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Interleukin 33, MIgG2a Fc-tagged
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Cat.#:Il33-2061MTag:GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il33 protein, GST-tagged
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Cat.#:Il33-358MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il33, His-tagged
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Cat.#:IL33-637MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse interleukin 33, His-tagged
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Cat.#:IL33-3045RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IL33 Protein
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Cat.#:Il33-50RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il33 protein, His-tagged
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Cat.#:Il33-583RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il33
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Cat.#:IL33-1034CTag:
Source (Host):E. coliSpecies:Canine
Product nameRecombinant Canine IL33 Protein
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Cat.#:IL33-322HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL33, His-tagged
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Cat.#:IL33-448HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 33, His-tagged
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Cat.#:IL33-58HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 33
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Cat.#:IL33-5226HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IL33 293 Cell Lysate
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Cat.#:IL33-4337HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human IL33 protein
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Involved Pathway

Il33 involved in several pathways and played different roles in them. We selected most pathways Il33 participated on our site, such as Cytosolic DNA-sensing pathway, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il33 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytosolic DNA-sensing pathway
POLR3GL; POLR3E; IFNB; IFNA12; POLR3B; IFNPHI1; DDX58; PYCARD; IFNA21; IFNA3
Influenza A
PYCARD; ACTB; IFNB1; IFNB; ACTG1; MAP2K4; IL1B; TYK2; NLRX1; IKBKE

Protein Function

Il33 has several biochemical functions, for example, cytokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il33 itself. We selected most functions Il33 had, and list some proteins which have the same functions with Il33. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein BMP3; OSTN; CTF1; IFNPHI1; GDF2; SP100; IFNA5; BMP4; SCG2; GRN
Function protein binding
Related Protein Ctsl; RAB22A; VRK1; MAP2K1; MASP2; PSIP1; KLF2; KIF14; DHX32; BLOC1S2A

Interacting Protein

Il33 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il33 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il33.
HIST1H2AG; IL1RL1; CRMP1; HIST1H2BC

Il33 Related Articles

Li, C; Mu, R; et al. Genetic variant in IL33 is associated with susceptibility to rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY 16:-(2014).
Tordesillas, L; Gomez-Casado, C; et al. Transport of Pru p 3 across gastrointestinal epithelium - an essential step towards the induction of food allergy?. CLINICAL AND EXPERIMENTAL ALLERGY 43:1374-1383(2013).

Il33 Related Gene Family

IL