Active Recombinant Human CD55 protein(Met1-Ser353), hFc-tagged
Cat.No. : | CD55-64H |
Product Overview : | Recombinant Human CD55 protein(NP_000565.1)(Met1-Ser353), fused with C-terminal hFc tag, was expressed in HEK293. |
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similar : | CD55 |
Alias : | CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); DAF, decay accelerating factor for complement (CD55, Cromer blood group system); complement decay-accelerating factor; CR; CROM; TC; CD55 antigen; DAF; |
Source : | HEK293 |
Species : | Human |
Conjugate : | C-hFc |
Tag : | C-hFc |
Protein length : | Met1-Ser353 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bioactivity : | Measured by its ability to bind human CD97-His in a functional ELISA. |
MolecularMass : | The recombinant human CD55/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 557 amino acids and has a predicted molecular mass of 61.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCD55/Fc monomer is approximately 95-105 kDa due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
GeneName : | CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) [ Homo sapiens ] |
GeneNameWeblink : | 1604 |
OfficialSymbol : | CD55 |
OfficialSymbolWeblink : | 1604 |
GeneID : | 1604 |
GeneIDWeblink : | 1604 |
mRNARefseq : | NM_000574 |
mRNARefseqWeblink : | NM_000574.3 |
ProteinRefseqWeblink : | NP_000565.1 |
MIMWeblink : | 125240 |
UniProtID : | P08174 |
UniProtIDWeblink : | P08174 |
Synonyms : | CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); DAF, decay accelerating factor for complement (CD55, Cromer blood group system); complement decay-accelerating factor; CR; CROM; TC; CD55 antigen; DAF; |
MIM : | 125240 |
Synonyms : | CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); DAF, decay accelerating factor for complement (CD55, Cromer blood group system); complement decay-accelerating factor; CR; CROM; TC; CD55 antigen; DAF; |
MIM : | 125240 |
Products Types
◆ Recombinant Protein | ||
CD55-2590H | Recombinant Human CD55 protein(231-350 aa), C-His-tagged | +Inquiry |
CD55-689H | Recombinant Human CD55 Protein, His-tagged | +Inquiry |
Cd55-6893M | Recombinant Mouse Cd55 protein(Met1-Thr361), His-tagged | +Inquiry |
CD55-01H | Recombinant Human CD55 Protein (35-353aa), C-His-tagged | +Inquiry |
CD55-164H | Recombinant Human CD55 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD55-1669MCL | Recombinant Mouse CD55 cell lysate | +Inquiry |
CD55-2531HCL | Recombinant Human CD55 cell lysate | +Inquiry |
CD55-1433RCL | Recombinant Rat CD55 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionGenetic variations in CD55 may influence susceptibility to complement-mediated disorders by affecting the protein's ability to regulate complement activation. This can lead to conditions like paroxysmal nocturnal hemoglobinuria (PNH).
CD55 has immunomodulatory functions beyond complement regulation, influencing T cell responses and contributing to the maintenance of immune tolerance.
CD55 protects cells from complement-mediated lysis by preventing the formation of membrane attack complexes. This contributes to immune evasion by pathogens and self-cells alike.
CD55 consists of extracellular domains responsible for interactions with complement proteins, particularly C3b and C4b. These interactions prevent the formation of membrane attack complexes on host cells.
CD55 dysregulation is associated with autoimmune disorders, where it may contribute to immune system overactivity. Additionally, some pathogens exploit CD55 to evade host immune responses.
Customer Reviews (3)
Write a reviewEfficient shipping and exceptional product quality. This company knows how to serve its customers.
Consistency is key in research, and this product delivers that every time.
We've tried various proteins, but this one stands out for its purity and performance.
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