Expand| Cat. No. : | CXCL14-25H |
| Product Overview : | Recombinant Human CXCL14 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 10.6 kDa. The Human BRAK contains fusion His tag at N-Terminus. The BRAK is purified by proprietary chromatographic techniques. |
| Description : | CXCL14 is involved in immunoregulatory and inflammatory processes. BRAK protein is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. CXCL14 displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. CXCL14 is involved in the homeostasis of monocyte-derived macrophages. |
| Source : | Escherichia Coli. |
| Amino Acid Sequence : | MKHHHHHHAS SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE |
| Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Formulation : | The protein was lyophilized from a concentrated (0.5mg/ml) solution containing 20mM Tris buffer & 20mM NaCl pH-7.5. |
| Solubility : | It is recommended to reconstitute the lyophilized CXCL14 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage : | Lyophilized BRAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BRAK should be stored at 4°Cbetween 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Gene Name : | CXCL14 chemokine (C-X-C motif) ligand 14 [ Homo sapiens ] |
| Synonyms : | CXCL14; chemokine (C-X-C motif) ligand 14; KS1; Kec; BMAC; BRAK; NJAC; MIP-2g; SCYB14; MGC10687; bolekine; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK);Small-inducible cytokine B14;C-X-C motif chemokine 14; UNQ240/PRO273; bolekine; CXC chemokine in breast and kidney; Chemokine BRAK; Chemokine BRAK; chemokine (C-X-C motif) ligand 14; small inducible cytokine subfamily B (Cys-X-Cys), member 14(BRAK) |
| Gene ID : | 9547 |
| mRNA Refseq : | NM_004887 |
| Protein Refseq : | NP_004878 |
| UniProt ID : | O95715 |
| Chromosome Location : | 5q31 |
| MIM : | 604186 |
| Pathway : | Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
| Function : | chemokine activity |
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