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Recombinant Human CXCL14, His-tagged

Cat.No. : CXCL14-25H
Product Overview : Recombinant Human CXCL14 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 10.6 kDa. The Human BRAK contains fusion His tag at N-Terminus. The BRAK is purified by proprietary chromatographic techniques.
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  • Gene Information
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Cat. No. : CXCL14-25H
Description : CXCL14 is involved in immunoregulatory and inflammatory processes. BRAK protein is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. CXCL14 displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. CXCL14 is involved in the homeostasis of monocyte-derived macrophages.
Source : Escherichia Coli.
Amino Acid Sequence : MKHHHHHHAS SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE
Physical Appearance : Sterile Filtered White lyophilized (freeze-dried) powder.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : The protein was lyophilized from a concentrated (0.5mg/ml) solution containing 20mM Tris buffer & 20mM NaCl pH-7.5.
Solubility : It is recommended to reconstitute the lyophilized CXCL14 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Storage : Lyophilized BRAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BRAK should be stored at 4°Cbetween 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Gene Name : CXCL14 chemokine (C-X-C motif) ligand 14 [ Homo sapiens ]
Synonyms : CXCL14; chemokine (C-X-C motif) ligand 14; KS1; Kec; BMAC; BRAK; NJAC; MIP-2g; SCYB14; MGC10687; bolekine; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK);Small-inducible cytokine B14;C-X-C motif chemokine 14; UNQ240/PRO273; bolekine; CXC chemokine in breast and kidney; Chemokine BRAK; Chemokine BRAK; chemokine (C-X-C motif) ligand 14; small inducible cytokine subfamily B (Cys-X-Cys), member 14(BRAK)
Gene ID : 9547
mRNA Refseq : NM_004887
Protein Refseq : NP_004878
UniProt ID : O95715
Chromosome Location : 5q31
MIM : 604186
Pathway : Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function : chemokine activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the relationship of CXCL14 protein to other genes or proteins? 09/14/2022

CXCL14 protein has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.

What is the specific role of CXCL14 protein in tumors? 02/18/2022

CXCL14 plays a dual role in tumors, on the one hand, it can inhibit the proliferation and metastasis of tumor cells, and on the other hand, it can promote the immune escape of tumor cells.

What are the types of mutations in CXCL14 protein? 05/03/2021

The types of mutations in CXCL14 protein include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

Could disease be treated by modulating CXCL14 protein levels? 09/12/2020

There are currently no drugs that directly regulate the levels of CXCL14 protein, but some diseases associated with CXCL14 protein can be treated by regulating its expression or inhibiting its activity.

How are mutations in CXCL14 protein detected and analyzed? 03/12/2020

Mutations in the CXCL14 protein can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

How to study the regulatory mechanism of CXCL14 protein? 12/23/2019

Studying the regulatory mechanism of CXCL14 protein requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Customer Reviews (3)

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Reviews
10/30/2022

    CXCL14 has important application value in the field of drug research and development, and has achieved certain research results.

    08/15/2022

      Good solubility, can be dissolved in a variety of buffers.

      03/06/2022

        I'm very satisfied. The quality is good and the price is affordable.

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