Recombinant Human TMEM173 protein, His-tagged
Cat.No. : | TMEM173-1436H |
Product Overview : | Recombinant Human TMEM173 aa. (Leu159~Pro373) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 30kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Leu159~Pro373 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >98% |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Isoelectric Point : | 5.8 |
Gene Name : | TMEM173 transmembrane protein 173 [ Homo sapiens (human) ] |
Official Symbol : | TMEM173 |
Synonyms : | TMEM173; transmembrane protein 173; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; stimulator of interferon genes protein; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; mitochondrial mediator of IRF3 activation |
Gene ID : | 340061 |
mRNA Refseq : | NM_198282.3 |
Protein Refseq : | NP_938023.1 |
UniProt ID : | Q86WV6 |
Products Types
◆ Recombinant Protein | ||
TMEM173-9325M | Recombinant Mouse TMEM173 Protein, His (Fc)-Avi-tagged | +Inquiry |
TMEM173-284H | Recombinant Human TMEM173 Protein, MYC/DDK-tagged | +Inquiry |
TMEM173-5855H | Recombinant Human TMEM173 Protein (Gly19-Ser260), N-His tagged | +Inquiry |
TMEM173-5856H | Recombinant Human TMEM173 Protein (Leu139-Ser379, H232R), N-His tagged | +Inquiry |
TMEM173-16951M | Recombinant Mouse TMEM173 Protein | +Inquiry |
◆ Lysates | ||
TMEM173-988HCL | Recombinant Human TMEM173 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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