Recombinant Mouse Tnfrsf10b Protein, Fc/His-tagged, FITC conjugated

• Cat.No.: Tnfrsf10b-3321MF
• Product Overview: FITC conjugated recombinant Mouse Tnfrsf10b (NP_064671.2) extracellular domain (Met 1-Ser 177), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His&Fc
• Form: Lyophilized
• Molecular Mass: The recombinant mouse TNFRSF10B/Fc chimera is a disulfide-linked homodimer. The reduced monomer consists of 373 amino acids and has a calculated molecular mass of 41.8 kDa. As a result of glycosylation, the apparent molecular mass of the TNFRSF10B/Fc monomer is approximately 50-55 kDa in SDS-PAGE under reducing conditions.
• Protein length: 373
• Endotoxin: < 1.0 EU/ μg of the protein as determined by the LAL method.
• Characteristic: Disulfide-linked homodimer
  Labeled with FITC via amines
  Excitation source: 488 nm spectral line, argon-ion laser
  Excitation Wavelength: 488 nm
  Emission Wavelength: 535 nm
• Stability: Samples are stable for up to 12 months from date of receipt at -70 centigrade.
• Storage: Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b [ Mus musculus ]
• Official Symbol: Tnfrsf10b
• Gene ID: 21933
• mRNA Refseq: NM_020275
• Protein Refseq: NP_064671

Reviews

08/11/2020

The combination of high-quality TNFRSF10B protein and excellent technical support provided by the manufacturer makes them the ideal choice for my research.

10/07/2018

The manufacturer's extensive experience and expertise in the field of TNFRSF10B protein research make them a trusted partner.

03/04/2017

The manufacturer's commitment to providing excellent technical support is highly valuable.

Q&As

How does TNFRSF10B activation induce apoptosis in cancer cells?

Activation of TNFRSF10B triggers apoptotic pathways, leading to programmed cell death in cancer cells.

Is TNFRSF10B involved in other diseases besides cancer?

TNFRSF10B has been implicated in certain autoimmune diseases and neurodegenerative disorders, highlighting its diverse roles in various physiological processes.

Can TNFRSF10B be used as a diagnostic marker for cancer?

TNFRSF10B expression levels may serve as a potential diagnostic marker for certain cancers, aiding in cancer detection and prognosis.

In what types of cancer is TNFRSF10B expression altered?

TNFRSF10B expression is often altered in various cancers, including breast cancer, colorectal cancer, and lung cancer.

Are there any side effects associated with targeting TNFRSF10B in cancer treatment?

Side effects may occur, and ongoing research aims to minimize these effects while maximizing the therapeutic benefits of targeting TNFRSF10B.