BMP2 Protein, bone morphogenetic protein 2


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Official Full Name bone morphogenetic protein 2
Background The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]
Synonyms BMP2; bone morphogenetic protein 2; BDA2; BMP2A; BMP-2A; bone morphogenetic protein 2A
    • Species :
    • Cattle
    • Chicken
    • Dog
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Mammalian Cell
    • Nicotiana Tobacum
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • S
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BMP2-129HG GMP Recombinant Human BMP2 protein, Fc-tagged HEK293 Fc
    Human BMP2&BMP7-709H Recombinant Human BMP2&BMP7 E.coli N/A
    Human BMP2-01H Recombinant Human BMP2 protein E.coli N/A
    Human BMP2-10249H Recombinant Human BMP2, GST-tagged E.coli GST
    Human BMP2-1119H Recombinant Human BMP2 protein E.coli
    Human BMP2-119HG GMP Recombinant Human BMP2 Protein CHO N/A
    Human BMP2-124H Recombinant Human BMP2, Fc-tagged CHO Fc
    Human BMP2-132H Human Bone morphogenetic Protein-2 (rDNA derived) Reference standard N/A
    Human BMP2-16H Recombinant Human BMP2, Fc tagged Human Cell Fc
    Human BMP2-17H Recombinant Human BMP2 Nicotiana Tobacum N/A
    Human BMP2-210H Recombinant Human BMP2 protein, His/S-tagged E.coli His/S
    Human BMP2-22H Recombinant Human Bone Morphogenetic Protein-2 CHO N/A
    Human BMP2-23H Recombinant Human BMP2 CHO N/A
    Human BMP2-259H Recombinant Human BMP2 protein, His-tagged E.coli His
    Human BMP2-260H Recombinant Human BMP2 Protein, GST-tagged Wheat Germ GST
    Human BMP2-261H Recombinant Human BMP2 Protein, GST-tagged Wheat Germ GST
    Human BMP2-3075HCL Recombinant Human BMP2 cell lysate Human Cell N/A
    Human BMP2-30H Human BMP2 Human N/A
    Human BMP2-31084TH Recombinant Human BMP2 N/A
    Human BMP2-560H Recombinant Human BMP2 protein, His & GST-tagged E.coli His/GST
    Human BMP2-561H Recombinant Human BMP2 protein, His-tagged E.coli His
    Human BMP2-56H Recombinant Human BMP2, HIgG1 Fc-tagged, mutant CHO Fc
    Human BMP2-867H Recombinant Human Bone Morphogenetic Protein 2, His-tagged E.coli His
    Mouse Bmp2-211M Recombinant Mouse Bmp2 protein, His/S-tagged E.coli His/S
    Mouse BMP2-2430M Recombinant Mouse BMP2 Protein Mammalian Cell His
    Mouse Bmp2-562M Recombinant Mouse Bmp2 protein, His-tagged E.coli His
    Rat Bmp2-212R Recombinant Rat Bmp2 protein, His/S-tagged E.coli His/S
    Rat Bmp2-565R Recombinant Rat Bmp2 protein, His-tagged E.coli His
    Rat BMP2-996R Recombinant Rat BMP2 Protein Mammalian Cell His
    Dog BMP2-558D Recombinant Dog BMP2 protein, His-tagged E.coli His
    Dog BMP2-559D Recombinant Dog BMP2 protein, His-tagged E.coli His
    Rabbit BMP2-566R Recombinant Rabbit BMP2 protein, His-tagged E.coli His
    Chicken BMP2-5929C Recombinant Chicken BMP2 Mammalian Cell His
    Cattle BMP2-557C Recombinant Cattle BMP2 protein, His & T7-tagged E.coli His/T7
    Pig BMP2-563P Recombinant Pig BMP2 protein, His-tagged E.coli His
    Pig BMP2-564P Recombinant Pig BMP2 protein, His-tagged E.coli His
    Cattle BMP2-567C Recombinant Cattle BMP2 protein, His-tagged E.coli His

    BMP2 involved in several pathways and played different roles in them. We selected most pathways BMP2 participated on our site, such as Cytokine-cytokine receptor interaction, Hedgehog signaling pathway, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CCL4; GM1987; TNFRSF9; IL20RA; TNFB; M17; CCL26; TNFRSF18; IL1R2; CXCR3
    Hedgehog signaling pathway WNT4; WNT7A; WNT8A; CSNK1DB; CSNK1G1; IHHB; GLI1; WNT1; WNT11R; SMO
    TGF-beta signaling pathway LEFTY2; ACVR1B; SMAD6; BMPR2B; TFDP1A; THBS1; TGFB1; SMAD3A; RBX1; MAPK3
    Hippo signaling pathway APC2; ITGB2L; ACTB; BMP2; WNT5A; SMAD2; FZD5; YWHAE; SNAI2; DLG1
    Signaling pathways regulating pluripotency of stem cells ESRRB; SOX2; NEUROG1; MAPK1; WNT6; WNT9B; HESX1; MAPK13; DLX5; SMAD5
    Pathways in cancer SMAD2; GNGT2; GLI2; RALBP1; BMP2; MMP9; HRAS; GNG5; PIK3CD; LAMA2
    Basal cell carcinoma APC2; WNT7B; WNT3A; GSK3B; FZD7; GLI2; TRP53; WNT2B; WNT8B; WNT2

    BMP2 has several biochemical functions, for example, BMP receptor binding, SMAD binding, co-receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP2 itself. We selected most functions BMP2 had, and list some proteins which have the same functions with BMP2. You can find most of the proteins on our site.

    Function Related Protein
    BMP receptor binding BMP7B; BMP8B; BMP2B; BMP2; BMP6; BMP7A; BMP3; BMP5; PYCARD; BMP8A
    co-receptor binding BMP4; NEO1; BMP2; DKK1; TFR2; HFE
    cytokine activity IFNPHI4; IFNA3; IL36G; WNT5A; IL17F; INHBA; Ccl12; CCL19A.1; HMGB1B; IL3
    growth factor activity INHA; INHBAB; GRN; BMP2B; FGF10; FGF16; NDR1; CD320; MSTN; GPI1
    phosphatase activator activity GTF2F1; BMP2; FRS2
    protein binding ITGA2; ZNF580; GIMAP7; TMEM106C; MALL; MCM2; YTHDC1; KPNB1; KCNA5; PRKCD
    protein heterodimerization activity BIRC5; HIST1H2AL; GTF2A1; BCL2L10; CLCF1; VEGFA; H2AFB3; CABYR; PDSS2; ATF4
    receptor binding GUSB; Artn; HAO2; LAMA2; CXCL1; TNFSF15; CRAT; NOS2; LBP; CSK
    retinol dehydrogenase activity RDH8; ADH7; DHRS3; SDR9C7; ADH4; RDH5; AKR1C3; BMP2; RDH10; ADH1
    transforming growth factor beta receptor binding LEFTY2; AMH; MSTN; GDF9; INHBAB; GDF15; INHBB; TGFBRAP1; INHBC; SPAW

    BMP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP2.


    Olivares-Navarrete, R; Hyzy, SL; et al. Coordinated regulation of mesenchymal stem cell differentiation on microstructured titanium surfaces by endogenous bone morphogenetic proteins. BONE 73:208-216(2015).
    Xu, LL; Liu, Y; et al. U0126 promotes osteogenesis of rat bone-marrow-derived mesenchymal stem cells by activating BMP/Smad signaling pathway. CELL AND TISSUE RESEARCH 359:537-545(2015).


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