csf1
Share
  • Official Full Name
  • colony stimulating factor 1 (macrophage)
  • Background
  • Macrophage colony-stimulating factor, or M-CSF, is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. (See colony-stimulating factor.) M-CSF binds to the Colony stimulating factor 1 receptor. It may also be involved in development of the placenta.
  • Synonyms
  • CSF1; colony stimulating factor 1 (macrophage); MCSF; MGC31930; macrophage colony-stimulating factor 1; CSF-1; lanimostim; OTTHUMP00000013362; OTTHUMP00000013363; OTTHUMP00000013364; OTTHUMP00000013365; macrophage colony stimulating factor; M-CSF
Cat.#:CSF1-339CTag:His
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CSF1 Protein, His-tagged
+Inquiry
Cat.#:CSF1-340CTag:Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CSF1 Protein, Fc-tagged
+Inquiry
Cat.#:CSF1-420HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1 Protein, His-Avi-tagged, Biotinylated
+Inquiry
Cat.#:CSF1-1962HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CSF1 Protein, GST-tagged
+Inquiry
Cat.#:CSF1-3337HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:CSF1-5383HTag:N/A
Source (Host):Hordeum vulgare (barley grain)Species:Human
Product nameRecombinant Human Colony Stimulating Factor 1 (macrophage)
+Inquiry
Cat.#:CSF1-4398BTag:
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine CSF1 Protein
+Inquiry
Cat.#:CSF1-4393CTag:
Source (Host):YeastSpecies:Chicken
Product nameRecombinant Chicken CSF1 Protein
+Inquiry
Cat.#:CSF1-289HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Colony Stimulating Factor 1 (Macrophage)
+Inquiry
Cat.#:CSF1-1875HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Colony Stimulating Factor 1 (macrophage)
+Inquiry
Cat.#:CSF1-177HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSF1 protein, His/S-tagged
+Inquiry
Cat.#:CSF1-216HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1, StrepII-tagged
+Inquiry
Cat.#:CSF1-26835THTag:His
Source (Host):Species:Human
Product nameRecombinant Human CSF1, His-tagged
+Inquiry
Cat.#:CSF1-32HTag:His
Source (Host):Barley grain (Hordeum vulgare)Species:Human
Product nameRecombinant Human CSF1, His-tagged
+Inquiry
Cat.#:CSF1-418HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CSF1
+Inquiry
Cat.#:CSF1-424HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1 Protein, Fc-tagged
+Inquiry
Cat.#:CSF1-425HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1 Protein, His-tagged
+Inquiry
Cat.#:CSF1-426HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human CSF1 Protein, His-tagged
+Inquiry
Cat.#:CSF1-427HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1 Protein
+Inquiry
Cat.#:CSF1-565HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1, His tagged
+Inquiry
Cat.#:CSF1-698HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSF1 protein, His & GST-tagged
+Inquiry
Cat.#:CSF1-96HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSF1, His-tagged
+Inquiry
Cat.#:Csf1-100MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Csf1
+Inquiry
Cat.#:Csf1-178MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Csf1 protein, His/S-tagged
+Inquiry
Cat.#:Csf1-290MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Csf1 protein
+Inquiry
Cat.#:CSF1-40MTag:
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse M-CSF
+Inquiry
Cat.#:CSF1-414MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Csf1, His tagged
+Inquiry
Cat.#:Csf1-522MTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Csf1
+Inquiry
Cat.#:Csf1-699MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Csf1 protein, His-tagged
+Inquiry
Cat.#:Csf1-95MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Csf1
+Inquiry
Cat.#:Csf1-12RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Csf1
+Inquiry
Cat.#:Csf1-13RTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Csf1
+Inquiry
Cat.#:Csf1-14RTag:N/A
Source (Host):CHOSpecies:Rat
Product nameRecombinant Rat Csf1
+Inquiry
Cat.#:Csf1-15RTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Csf1
+Inquiry
Cat.#:Csf1-179RTag:His/S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Csf1 protein, His/S-tagged
+Inquiry
Cat.#:CSF1-4112CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CSF1
+Inquiry
Cat.#:CSF1-033ETag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSF1 (33-190aa), Met tagged
+Inquiry
Cat.#:Csf1-041ETag:N/A
Source (Host):MouseSpecies:Mouse
Product nameRecombinant Mouse Csf1 (33-262aa), Met tagged
+Inquiry
Cat.#:CSF1-167HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Colony Stimulating Factor 1 (Macrophage)
+Inquiry
Cat.#:CSF1-339HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Colony Stimulating Factor 1 (macrophage)
+Inquiry
Cat.#:CSF1-357HTag:N/A
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Colony Stimulating Factor 1 (macrophage)
+Inquiry
Cat.#:CSF1-1934HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1 cell lysate
+Inquiry
Cat.#:CSF1-001MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CSF1 cell lysate
+Inquiry
Cat.#:CSF1-110HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human CSF1 Protein
+Inquiry
Cat.#:CSF1-94HTag:
Source (Host):Species:Human
Product nameHuman Macrophage Colony Stimulating Factor(rDNA derived) Reference standard
+Inquiry

Involved Pathway

CSF1 involved in several pathways and played different roles in them. We selected most pathways CSF1 participated on our site, such as Cytokine-cytokine receptor interaction, Cytokines and Inflammatory Response, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CNTFR; TSLP; IL2RB; IL13RA1; Ccl21c; LIF; IL6ST; IL3RA; IFNA17; IFNA13
Cytokines and Inflammatory Response
CSF2; CSF3; CSF1
Hematopoietic cell lineage
MME; HLA-DRB4; CD8B; GP1BA; CD1B; IL11; CD4; IL7; IL7R; EPOR
Integrins in angiogenesis
CSF1; EDIL3; ANGPTL3; CSF1R; MFGE8
Osteoclast differentiation
CYBB; TNFRSF1A; SFPI1; FCGR2C; CSF1R; IKBKG; MAP2K1; TREM2; IFNAR2; LILRB2
PI3K-Akt signaling pathway
CSH2; EFNA4; CDC37; CSF3R; EFNA3; EFNA2; PIK3AP1; CSH1; CSF1R; CHAD
Rap1 signaling pathway
PFN4; EFNA4; LOC608458; RGS14; CSF1; EFNA2
Ras signaling pathway
PLA2G2F; FGFR3; SHC4; RASAL3; GNB2; PIK3R5; PIK3CB; GNGT1; PLA2G12B; AKT2

Protein Function

CSF1 has several biochemical functions, for example, cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF1 itself. We selected most functions CSF1 had, and list some proteins which have the same functions with CSF1. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein IL4; INHBB; BMP7A; IL6; Kitl; IL17A/F2; IL1B; IFNA5; TNFSF10; NODAL
Function growth factor activity
Related Protein FGF6B; FGF12; EFEMP1; BMP2; BMP16; BMP7A; IL34; BMP5; NDP; OSM
Function macrophage colony-stimulating factor receptor binding
Related Protein CSF1; IL34; STAP1
Function protein binding
Related Protein C5orf30; C2orf65; SERP1; STAMBPL1; MRPS31; LAIR1; SIN3A; SDC4; ARL2; MT3
Function protein homodimerization activity
Related Protein UBE4A; FBXO4; PAH; GLIPR2; CUL3; CAMK2B; CCL5; PAFAH1B2; CHMP1A; CAT

Interacting Protein

CSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF1.
SGTA; FHL3; NOTCH2NL; adhC; MYC

CSF1 Related Articles

Moffat, L; Rothwell, L; et al. Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 47:123-128(2014).
Sauter, KA; Pridans, C; et al. Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. JOURNAL OF LEUKOCYTE BIOLOGY 96:265-274(2014).