Human PRMT7 Knockdown Cell Lysate

• Cat.No.: PRMT7-281HKCL
• Product Overview: WB-validated PRMT7 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 78 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg PRMT7 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: PRMT7 protein arginine methyltransferase 7 [ Homo sapiens (human) ]
• Official Symbol: PRMT7
• Synonyms: PRMT7; protein arginine methyltransferase 7; protein arginine N-methyltransferase 7; FLJ10640; KIAA1933; histone-arginine N-methyltransferase PRMT7; myelin basic protein-arginine N-methyltransferase; [Myelin basic protein]-arginine N-methyltransferase PRMT7
• Gene ID: 54496
• mRNA Refseq: NM_001184824
• Protein Refseq: NP_001171753
• MIM: 610087
• UniProt ID: Q9NVM4