Recombinant Human CXCL1 protein, His & GST-tagged
Cat.No. : | CXCL1-769H |
Product Overview : | Recombinant Human CXCL1 aa. (Ala35~Asn107 (Accession # P09341)) fused with N-terminal His & GST tag was produced in E. coli cells. |
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Description : | This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. |
Source : | E. coli |
Species : | Human |
Tag : | His&GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 40.0kDa |
Protein length : | Ala35~Asn107 (Accession # P09341) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Characteristic : | The isoelectric point is 8.3. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4 |
Gene Name : | CXCL1 C-X-C motif chemokine ligand 1 [ Homo sapiens (human) ] |
Official Symbol : | CXCL1 |
Synonyms : | CXCL1; C-X-C motif chemokine ligand 1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a; growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha(1-73); GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); MGSA alpha; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein; melanoma growth stimulating activity, alpha; melanoma growth stimulatory activity alpha; neutrophil-activating protein 3 |
Gene ID : | 2919 |
mRNA Refseq : | NM_001511.3 |
Protein Refseq : | NP_001502.1 |
UniProt ID : | P09341 |
Products Types
◆ Recombinant Protein | ||
CXCL1-195H | Recombinant Human CXCL1 protein(Ala35-Asn107), His&NusA-tagged | +Inquiry |
CXCL1-272C | Active Recombinant Human CXCL1 Protein | +Inquiry |
CXCL1-3224R | Recombinant Rat CXCL1 protein(Ala25-Lys96) | +Inquiry |
Cxcl1-33M | Active Recombinant Mouse Cxcl1 Protein (Asn29-Lys96), Animal-free, Carrier-free | +Inquiry |
CXCL1-178C | Recombinant Cynomolgus Monkey CXCL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CXCL1-27707TH | Native Human CXCL1 | +Inquiry |
◆ Lysates | ||
CXCL1-425HCL | Recombinant Human CXCL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewEfficient delivery, great service.
Product as described, perfect.
Reliable for protein work.
Q&As (7)
Ask a questionTherapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.
It mediates inflammation by promoting leukocyte migration and activation.
In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.
CXCL1 contributes to angiogenesis, supporting new blood vessel formation.
CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.
CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.
CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.
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