Recombinant Human Fibroblast Growth Factor 4

• Cat.No.: FGF4-681H
• Product Overview: Recombinant Human FGF4is Expressed in HEK 293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Non
• Description: FGF4 is expressedin human 293 cells as a monomeric glycoprotein with an apparent MW 17 and 27kDa. This cytokine is produced in a human cell expression system withserum-free, chemically defined media. Authentic glycosylation contributes tostability in cell growth media and other applications. The cytokine isgreater than 95% pure.
• MolecularWeight: 17 and 27 kDamonomer, glycosylated
• Purity: > 95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue.
• Endotoxin Level: Endotoxin Free<1 EU/µg
• Biological Activity: 0.50.25 to 1.25ng/mL ED50
• Specific Activity: The specificactivity was determined by the dose-dependent stimulation of theproliferation of the Balb/3T3 cell line.
• OfficialSymbol: FGF4

Gene Information

• Gene Name: FGF4 fibroblast growth factor 4[ Homo sapiens ]
• Synonyms: FGF4; fibroblastgrowth factor 4; HST; KFGF; HST-1;HSTF1; K-FGF; HBGF-4; fibroblast growth factor 4; FGF-4; HSTF-1; oncogene HST;OTTHUMP00000237541; kaposi sarcoma oncogene; transforming protein KS3; heparin-bindinggrowth factor 4; heparin secretory transforming protein 1; heparinsecretory-transforming protein 1; fibroblast growth factor 4 splice isoform;human stomach cancer, transforming; factor from FGF-related oncogene
• Gene ID: 2249
• mRNA Refseq: NM_002007
• Protein Refseq: NP_001998
• MIM: 164980
• UniProt ID: P08620
• Chromosome Location: 11q13.3
• Pathway: Downstream signalingof activated FGFR; ESC Pluripotency Pathways; Endochondral Ossification; FGFRligand binding and activation; FRS2-mediated cascade; IRS-mediatedsignalling; IRS-related events; Insulin receptor signalling cascade; MAPKsignaling pathway; Melanoma; MicroRNAs in cardiomyocyte hypertrophy; PI-3Kcascade; Pathways in cancer; Phospholipase C-mediated cascade
• Function: fibroblast growthfactor receptor binding; growth factor activity; heparin binding; proteintyrosine kinase activity