Recombinant Human Fibroblast Growth Factor 4
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Cat.No. : | FGF4-681H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human FGF4is Expressed in HEK 293 cells. |
Description : | FGF4 is expressedin human 293 cells as a monomeric glycoprotein with an apparent MW 17 and 27kDa. This cytokine is produced in a human cell expression system withserum-free, chemically defined media. Authentic glycosylation contributes tostability in cell growth media and other applications. The cytokine isgreater than 95% pure. |
Source : | HEK 293 cells |
Species : | Human |
MolecularWeight : | 17 and 27 kDamonomer, glycosylated |
Purity : | > 95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue. |
Endotoxin Level : | Endotoxin Free<1 EU/µg |
Biological Activity : | 0.50.25 to 1.25ng/mL ED50 |
Specific Activity : | The specificactivity was determined by the dose-dependent stimulation of theproliferation of the Balb/3T3 cell line. |
OfficialSymbol : | FGF4 |
PDBrendering based on 1ijt. : |
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Gene Name : | FGF4 fibroblast growth factor 4[ Homo sapiens ] |
Synonyms : | FGF4; fibroblastgrowth factor 4; HST; KFGF; HST-1;HSTF1; K-FGF; HBGF-4; fibroblast growth factor 4; FGF-4; HSTF-1; oncogene HST;OTTHUMP00000237541; kaposi sarcoma oncogene; transforming protein KS3; heparin-bindinggrowth factor 4; heparin secretory transforming protein 1; heparinsecretory-transforming protein 1; fibroblast growth factor 4 splice isoform;human stomach cancer, transforming; factor from FGF-related oncogene |
Gene ID : | 2249 |
mRNA Refseq : | NM_002007 |
Protein Refseq : | NP_001998 |
MIM : | 164980 |
UniProt ID : | P08620 |
Chromosome Location : | 11q13.3 |
Pathway : | Downstream signalingof activated FGFR; ESC Pluripotency Pathways; Endochondral Ossification; FGFRligand binding and activation; FRS2-mediated cascade; IRS-mediatedsignalling; IRS-related events; Insulin receptor signalling cascade; MAPKsignaling pathway; Melanoma; MicroRNAs in cardiomyocyte hypertrophy; PI-3Kcascade; Pathways in cancer; Phospholipase C-mediated cascade |
Function : | fibroblast growthfactor receptor binding; growth factor activity; heparin binding; proteintyrosine kinase activity |
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