Recombinant Human VASP Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human VASP Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : VASP-1570H
Product Overview : VASP MS Standard C13 and N15-labeled recombinant protein (NP_003361) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 40.3 kDa
AA Sequence : MSETVICSSR ATVMLYDDGN KRWLPAGTGP QAFSRVQIYH NPTANSFRVV GRKMQPDQQV VINCAIVRGV KYNQATPNFH QWRDARQVWG LNFGSKEDAA QFAAGMASAL EALEGGGPPP PPALPTWSVP NGPSPEEVEQ QKRQQPGPSE HIERRVSNAG GPPAPPAGGP PPPPGPPPPP GPPPPPGLPP SGVPAAAHGA GGGPPPAPPL PAAQGPGGGG AGAPGLAAAI AGAKLRKVSK QEEASGGPTA PKAESGRSGG GGLMEEMNAM LARRRKATQV GEKTPKDESA NQEEPEARVP AQSESVRRPW EKNSTTLPRM KSSSSVTTSE TQPCTPSSSD YSDLQRVKQE LLEEVKKELQ KVKEEIIEAF VQELRKRGSP TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : VASP vasodilator-stimulated phosphoprotein [ Homo sapiens (human) ]
Official Symbol : VASP
Synonyms : VASP; vasodilator-stimulated phosphoprotein;
Gene ID : 7408
mRNA Refseq : NM_003370
Protein Refseq : NP_003361
MIM : 601703
UniProt ID : P50552

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