cd28
Share
  • Official Full Name
  • CD28 CD28 molecule
  • Synonyms
  • CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290;
Cat.#:CD28-32HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28 protein, Biotin-labelled
+Inquiry
Cat.#:CD28-338HTag:Avi|Fc
Source (Host):HEK293Species:Human / Cynomolgus / Rhesus Monkey
Product nameRecombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, Fc & Avi-tagged, Biotinylated
+Inquiry
Cat.#:CD28-0772HTag:N/A
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD28 Protein
+Inquiry
Cat.#:CD28-0773HTag:His|Flag|StrepII
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD28 Protein, His-Flag-StrepII-Tagged
+Inquiry
Cat.#:CD28-0774HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD28 Protein, GST-Tagged
+Inquiry
Cat.#:CD28-1593HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human CD28 Molecule
+Inquiry
Cat.#:Cd28-1712MTag:Fc|His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse CD28 Antigen, Fc-His
+Inquiry
Cat.#:CD28-336HTag:Mouse|IgG2a|Fc
Source (Host):HEK293Species:Human/Cynomolgus/Rhesus macaque
Product nameRecombinant Human/Cynomolgus/Rhesus macaque CD28 protein, Mouse IgG2a Fc-tagged, low endotoxin
+Inquiry
Cat.#:CD28-337HTag:His
Source (Host):HEK293Species:Human/Cynomolgus/Rhesus macaque
Product nameRecombinant Human/Cynomolgus/Rhesus macaque CD28 protein, His-tagged
+Inquiry
Cat.#:CD28-339MTag:human|IgG1|Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28 protein, Fc-tagged
+Inquiry
Cat.#:CD28-142HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, Fc-tagged
+Inquiry
Cat.#:CD28-181HTag:DDK|His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, DDK/His-tagged
+Inquiry
Cat.#:CD28-182HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, Fc-tagged
+Inquiry
Cat.#:CD28-212HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, MIgG2a Fc-tagged
+Inquiry
Cat.#:CD28-321HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein
+Inquiry
Cat.#:CD28-378HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, HIgG1 Fc-tagged
+Inquiry
Cat.#:CD28-3908HTag:Avi|Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, Fc & Avi-tagged, Biotinylated
+Inquiry
Cat.#:CD28-3909HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28, Fc tagged
+Inquiry
Cat.#:CD28-3910HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28, His tagged
+Inquiry
Cat.#:CD28-566HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD28, Fc-tagged, Biotinylated
+Inquiry
Cat.#:CD28-232MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse CD28, MIgG2a Fc-tagged
+Inquiry
Cat.#:Cd28-4008MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd28, His tagged
+Inquiry
Cat.#:CD28-640MTag:Fc|His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28, Fc-His tagged
+Inquiry
Cat.#:Cd28-661MTag:His|GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cd28 protein, His & GST-tagged
+Inquiry
Cat.#:CD28-1099RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD28 Protein, Fc-tagged
+Inquiry
Cat.#:CD28-1100RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD28 Protein, His-tagged
+Inquiry
Cat.#:CD28-1244RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CD28 Protein
+Inquiry
Cat.#:CD28-1204CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD28 Protein, Fc-tagged
+Inquiry
Cat.#:CD28-387CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD28 Protein, His-tagged
+Inquiry
Cat.#:CD28-733RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD28 Protein, His-tagged
+Inquiry
Cat.#:CD28-6863CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CD28
+Inquiry
Cat.#:CD28-2013HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 cell lysate
+Inquiry
Cat.#:CD28-2002MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28 cell lysate
+Inquiry
Cat.#:Kit-1705Tag:N/A
Source (Host):Species:
Product nameCD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit
+Inquiry

Involved Pathway

CD28 involved in several pathways and played different roles in them. We selected most pathways CD28 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
NEO1; CLDN7A; NFASC; NEO1A; ITGAV; NLGN3; PTPRM; CLDN15A; CDH2; HLA-DRB3
T cell receptor signaling pathway
FYN; GRAP2; PDCD1; DLG1; NFKBIA; TNF; TEC; MAPK12; PIK3R3; DBNLB
Intestinal i
CCL28; ICOS; IL4; BLB1; CCL27B; HLA-DMA; BMA1; ITGA4; TNFSF13; MAP3K14
ne network for IgA production
TNFRSF17; CD40LG; CD86; CD28; TNFRSF13B; HLA-DPB1; ITGB7; ITGA4; MAP3K14; HLA-DOB
Type I diabetes mellitus
IL1B; INS2; CD80; PTPRN; IFNG; CD28; Fasl; HLA-DMB; HSPD1; HLA-DOB
Measles
IL6; OAS1; IL4; TAB2; IL1B; CBLB; STAT3; TP73; Fasl; cgr2b
Autoi
HLA-DPA1; HLA-A; FAS; TSHB; FASLG; PRF1; IFNA21; IFNA7; IL5; IFNA4
ne thyroid disease
HLA-DRB1; H2-AA; TSHB; CD28; H2-AB1; HLA-A; IFNA5; HLA-DRA; IFNA8; HLA-DQA1
Systemic lupus erythematosus
HLA-DMB; HIST1H3C; HIST1H2BN; FCGR3B; HIST1H2AE; SNRPB; H2AFV; CD40LG; ACTN4; HIST2H2AA4
Rheumatoid arthritis
H2-AB1; ATP6V1B1; CCL3L3; HLA-DQB1; TNFSF13; ATP6V0E1; TNFRSF11A; ATP6V0E; HLA-DOB; CD80
Allograft rejection
HLA-DOA; HLA-DPB1; CD86; IL4; IL5; HLA-DMB; CD80; HLA-DPA1; MICA; HLA-E
Graft-versus-host disease
H2-AA; KIR2DL3; HLA-DMB; HLA-DMA; HLA-E; HLA-F; HLA-G; HLA-DQA1; KIR3DL2; IL1B
Viral myocarditis
H2-AA; CASP9; LAMA2; HLA-DOB; RAC3; RAC1; HLA-DRB5; EIF4G3; CD40; CXADR

Protein Function

CD28 has several biochemical functions, for example, SH3/SH2 adaptor activity, coreceptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD28 itself. We selected most functions CD28 had, and list some proteins which have the same functions with CD28. You can find most of the proteins on our site.
Function
Related Protein
Function SH3/SH2 adaptor activity
Related Protein KHDRBS1; RUSC1; GRAP; PTPN11; SH3BGRL; CHN1; HSH2D; SH2D3C; EPS8; CRKL
Function coreceptor activity
Related Protein CD8A; CD4; PVRL2; RAMP1; RGMB; HFE2; ACKR3B; RAMP3; CCR8; CXCR4
Function identical protein binding
Related Protein SERPINA1A; BIRC5; VEGFA; STK10; PFKM; PRMT1; PRPS2; ATXN3; PARK2; PSMA7
Function protease binding
Related Protein PANX1; STIM1; PYCARD; TRIP4; CAST; ADRM1; A2M; KIT; BCL2; SEMG2
Function protein binding
Related Protein GTF2A1; PLCB4; TIMP1; CBL; C10orf28; CEP70; DUSP19; PTCH1; MED28; ZNF410

Interacting Protein

CD28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD28 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD28.
PIK3R1; GRAP2; CD80; PIK3R1; Pik3r1; GRB2; PRKCQ

CD28 Related Articles

Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).

CD28 Related Gene Family

Immunoglobulins