cd28
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  • Official Full Name
  • CD28 CD28 molecule
  • Synonyms
  • CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290;
Cat.#:CD28-32HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28 protein, Biotin-labelled
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Cat.#:CD28-336HTag:MIgG2a Fc
Source (Host):HEK293Species:Human / Cynomolgus / Rhesus Monkey
Product nameRecombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, MIgG2a Fc-tagged, low endotoxin
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Cat.#:CD28-337HTag:His
Source (Host):HEK293Species:Human / Cynomolgus / Rhesus Monkey
Product nameRecombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, His-tagged
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Cat.#:CD28-338HTag:Fc/Avi
Source (Host):HEK293Species:Human / Cynomolgus / Rhesus Monkey
Product nameRecombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, Fc & Avi-tagged, Biotinylated
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Cat.#:CD28-339MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28 Protein, Fc-tagged
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Cat.#:CD28-0772HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD28 Protein
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Cat.#:CD28-0773HTag:His-Flag-StrepII
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD28 Protein, His-Flag-StrepII-Tagged
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Cat.#:CD28-0774HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD28 Protein, GST-Tagged
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Cat.#:CD28-1593HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human CD28 Molecule
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Cat.#:Cd28-1712MTag:FC/His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse CD28 Antigen, Fc-His
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Cat.#:CD28-142HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, Fc-tagged
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Cat.#:CD28-181HTag:DDK/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, DDK/His-tagged
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Cat.#:CD28-182HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, Fc-tagged
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Cat.#:CD28-212HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, MIgG2a Fc-tagged
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Cat.#:CD28-321HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein
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Cat.#:CD28-378HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, HIgG1 Fc-tagged
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Cat.#:CD28-3908HTag:Fc/Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, Fc & Avi-tagged, Biotinylated
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Cat.#:CD28-3909HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28, Fc tagged
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Cat.#:CD28-3910HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28, His tagged
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Cat.#:CD28-566HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD28, Fc-tagged, Biotinylated
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Cat.#:CD28-232MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse CD28, MIgG2a Fc-tagged
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Cat.#:Cd28-4008MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd28, His tagged
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Cat.#:CD28-640MTag:FC/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28, Fc-His tagged
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Cat.#:Cd28-661MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cd28 protein, His & GST-tagged
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Cat.#:CD28-1099RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD28 Protein, Fc-tagged
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Cat.#:CD28-1100RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD28 Protein, His-tagged
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Cat.#:CD28-1244RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CD28 Protein
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Cat.#:CD28-1204CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD28 Protein, Fc-tagged
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Cat.#:CD28-387CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD28 Protein, His-tagged
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Cat.#:CD28-733RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD28 Protein, His-tagged
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Cat.#:CD28-6863CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CD28
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Cat.#:CD28-2013HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 cell lysate
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Cat.#:CD28-2002MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28 cell lysate
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Cat.#:Kit-1705Tag:
Source (Host):Species:
Product nameCD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit
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Involved Pathway

CD28 involved in several pathways and played different roles in them. We selected most pathways CD28 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
JAM2; MAG; CLDN2; CLDN6; PVRL2; H2-Q10; CLDN15A; CLDN11B; PVRL3; ALCAM
T cell receptor signaling pathway
PIK3CG; EVLB; MAPK12; CBL; MAP3K7; MAP2K2; PPP3CA; PPP3CC; SOS1; PAK2
Intestinal i
LTBR; HLA-DQB1; IL15; HLA-DRB5; CD28; MHC2DCB; IL4; TGFB1; BLB2; TNFSF13
ne network for IgA production
ICOSLG; CD40; MAP3K14; CD80; LTBR; BMA2; H2-AA; CD28; CD86; BLB2
Type I diabetes mellitus
PTPRN2; HLA-E; Il2; HLA-DPA1; FASLG; HLA-DQB1; HLA-DOB; HLA-DQA1; IL12A; H2-Q10
Measles
TLR2; IFNA10; TNFAIP3; PIK3CA; IFNGR2; SH2D1A; CCNE1; PIK3R2; MSN; HSPA1B
Autoi
TG; HLA-C; IFNA12; IFNA8; CD80; IFNA7; IL5; IFNA5; IFNA1; H2-AB1
ne thyroid disease
IFNA21; HLA-DRB1; H2-AB1; Ifna15; FAS; HLA-DOA; HLA-DOB; HLA-DRB5; CD86; HLA-DPB1
Systemic lupus erythematosus
C6; H2-AB1; HIST1H2AE; HIST1H2AB; HLA-DOB; TNF; C8G; HIST1H2BJ; GM14479; HIST1H2BI
Rheumatoid arthritis
ATP6V1E1; ATP6V1E2; ATP6V0E2; CXCL12; CCL5; ITGAL; CCL2; CD28; FLT1; FOS
Allograft rejection
IL12B; HLA-F; HLA-DPA1; HLA-A; CD40LG; CD86; Fasl; HLA-DRB1; HLA-DMB; FAS
Graft-versus-host disease
HLA-DOB; HLA-G; HLA-C; TNF; IFNG; CD86; HLA-DMA; KIR3DL1; IL1A; HLA-B
Viral myocarditis
CAV1; FYN; ACTG1; MYH7; H2-AB1; HLA-DOB; HLA-DQB1; HLA-DQA1; ACTB; SGCG

Protein Function

CD28 has several biochemical functions, for example, SH3/SH2 adaptor activity, coreceptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD28 itself. We selected most functions CD28 had, and list some proteins which have the same functions with CD28. You can find most of the proteins on our site.
Function
Related Protein
Function SH3/SH2 adaptor activity
Related Protein NCK2; NCK1; ITSN2; EPS8; SH3BP2; CHN1; SH2D1A; GRB14; SKAP2; GRAP
Function coreceptor activity
Related Protein HFE2; CCR5; PVRL2; CD8A; LRP5; ZP2; CD4; CXCR6; PVRL1; CCR8
Function identical protein binding
Related Protein FHL2; LZTFL1; ZNF3; FHOD1; SYNE1; ZNHIT6; GPSM2; GBP5; GRASP; EED
Function protease binding
Related Protein SERPINA1A; Cstb; FADD; Serpina1b; PEO1; ADAM8A; TRP53; C10orf2; TTN; CST3
Function protein binding
Related Protein PELO; MEN1; ASB6; SIGLEC6; TMSB10; WBP2NL; FERMT2; IL10RA; PAN3; CSTF2

Interacting Protein

CD28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD28 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD28.
PIK3R1; GRAP2; CD80; PIK3R1; Pik3r1; GRB2; PRKCQ

CD28 Related Articles

Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).

CD28 Related Gene Family

Immunoglobulins