cd28
Share
  • Official Full Name
  • CD28 CD28 molecule
  • Synonyms
  • CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290;
Cat.#:CD28-32HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28 protein, Biotin-labelled
+Inquiry
Cat.#:CD28-336HTag:MIgG2a Fc
Source (Host):HEK293Species:Human / Cynomolgus / Rhesus Monkey
Product nameRecombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, MIgG2a Fc-tagged, low endotoxin
+Inquiry
Cat.#:CD28-337HTag:His
Source (Host):HEK293Species:Human / Cynomolgus / Rhesus Monkey
Product nameRecombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, His-tagged
+Inquiry
Cat.#:CD28-338HTag:Fc/Avi
Source (Host):HEK293Species:Human / Cynomolgus / Rhesus Monkey
Product nameRecombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, Fc & Avi-tagged, Biotinylated
+Inquiry
Cat.#:CD28-339MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28 Protein, Fc-tagged
+Inquiry
Cat.#:CD28-0772HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD28 Protein
+Inquiry
Cat.#:CD28-0773HTag:His-Flag-StrepII
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD28 Protein, His-Flag-StrepII-Tagged
+Inquiry
Cat.#:CD28-0774HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD28 Protein, GST-Tagged
+Inquiry
Cat.#:CD28-1593HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human CD28 Molecule
+Inquiry
Cat.#:Cd28-1712MTag:FC/His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse CD28 Antigen, Fc-His
+Inquiry
Cat.#:CD28-142HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, Fc-tagged
+Inquiry
Cat.#:CD28-181HTag:DDK/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, DDK/His-tagged
+Inquiry
Cat.#:CD28-182HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, Fc-tagged
+Inquiry
Cat.#:CD28-212HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, MIgG2a Fc-tagged
+Inquiry
Cat.#:CD28-321HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein
+Inquiry
Cat.#:CD28-378HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD28, HIgG1 Fc-tagged
+Inquiry
Cat.#:CD28-3908HTag:Fc/Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 Protein, Fc & Avi-tagged, Biotinylated
+Inquiry
Cat.#:CD28-3909HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28, Fc tagged
+Inquiry
Cat.#:CD28-3910HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28, His tagged
+Inquiry
Cat.#:CD28-566HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD28, Fc-tagged, Biotinylated
+Inquiry
Cat.#:CD28-232MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse CD28, MIgG2a Fc-tagged
+Inquiry
Cat.#:Cd28-4008MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd28, His tagged
+Inquiry
Cat.#:CD28-640MTag:FC/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28, Fc-His tagged
+Inquiry
Cat.#:Cd28-661MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cd28 protein, His & GST-tagged
+Inquiry
Cat.#:CD28-1099RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD28 Protein, Fc-tagged
+Inquiry
Cat.#:CD28-1100RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD28 Protein, His-tagged
+Inquiry
Cat.#:CD28-1244RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CD28 Protein
+Inquiry
Cat.#:CD28-1204CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD28 Protein, Fc-tagged
+Inquiry
Cat.#:CD28-387CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD28 Protein, His-tagged
+Inquiry
Cat.#:CD28-733RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD28 Protein, His-tagged
+Inquiry
Cat.#:CD28-6863CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CD28
+Inquiry
Cat.#:CD28-2013HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD28 cell lysate
+Inquiry
Cat.#:CD28-2002MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD28 cell lysate
+Inquiry
Cat.#:Kit-1705Tag:
Source (Host):Species:
Product nameCD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit
+Inquiry

Involved Pathway

CD28 involved in several pathways and played different roles in them. We selected most pathways CD28 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
CD40; HLA-DQA1; CNTN1; ICOS; CLDND; MPZ; CLDN9; CD58; NLGN2B; NCAM1
T cell receptor signaling pathway
AKT1; GRB2; CBL; MAP3K7; LCP2; AKT2; NCK1; VAV2; MAPK3; NFKB1
Intestinal i
HLA-DRA; Il2; TNFRSF17; HLA-DMB; HLA-DPB1; IL-15RA; CXCR4A; ITGA4; HLA-DRB5; IL4
ne network for IgA production
TNFSF13; CD86; BLB2; TNFRSF17; HLA-DRA; LTBR; CD40; Icosl; HLA-DRB5; IL15RA
Type I diabetes mellitus
H2-AA; PRF1; IL12B; IL1B; CD86; IFNG; HLA-DPA1; Il2; HLA-DRB1; HLA-C
Measles
STAT1; NFKB1; PIK3CB; PIK3R1; CCNE1; IL2RG; IL1A; IFNA2; MSN; IFNA14
Autoi
IFNA5; HLA-DMB; Ifna11; HLA-DRB3; IFNA2; HLA-DRB5; IFNA12; HLA-DRB4; HLA-DPB1; H2-AB1
ne thyroid disease
IFNA12; Ifna15; IFNA4; HLA-G; HLA-DOB; IFNA13; GZMB; IFNA10; HLA-DPB1; CD86
Systemic lupus erythematosus
CD86; SSB; TNF; HIST1H3I; H2AFY2; H3F3C; HIST1H4F; HIST2H4A; HIST1H2BN; ACTN2
Rheumatoid arthritis
Ctsl; ATP6V1A; HLA-DRA; ATP6V1C2; CXCL5; ATP6V0A4; ATP6V0D2; ACP5; ATP6V1E1; TNF
Allograft rejection
CD86; HLA-DMA; HLA-DQB1; IL12A; HLA-B; GZMB; HLA-E; HLA-DRB5; HLA-DRB1; Il2
Graft-versus-host disease
HLA-F; KIR2DL1; IL1A; HLA-DRB1; PRF1; HLA-G; HLA-DRB5; KIR3DL1; HLA-DQB1; TNF
Viral myocarditis
SGCB; HLA-DQA2; MYH7; BID; CAV1; CD80; HLA-B; HLA-DPA1; PRF1; EIF4G3

Protein Function

CD28 has several biochemical functions, for example, SH3/SH2 adaptor activity, coreceptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD28 itself. We selected most functions CD28 had, and list some proteins which have the same functions with CD28. You can find most of the proteins on our site.
Function
Related Protein
Function SH3/SH2 adaptor activity
Related Protein CRKL; SH2B2; SLA; SLA2; CHN2; TOB1; SRC; SOCS2; GAB1; SH2D3C
Function coreceptor activity
Related Protein IGSF1; RAMP1; LY96; CD8A; ACVR2A; CCR5; LRP5; ZP2; CXCR6; RAMP2
Function identical protein binding
Related Protein ESR1; BRAF; ABCD1; PNMA5; MRFAP1L1; BAIAP2; CBX3; HSD17B10; MLL1; IMPA1
Function protease binding
Related Protein ECM1; TIMP2A; ALPI; CCDC71L; IL1R1; FURIN; ADRM1; CRADD; BRCA2; F3
Function protein binding
Related Protein DRAP1; PMF1; ZNF302; LRRFIP2; ITGA1; FATE1; DDB1; CD274; ARNT; CTPS2

Interacting Protein

CD28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD28 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD28.
PIK3R1; GRAP2; CD80; PIK3R1; Pik3r1; GRB2; PRKCQ

CD28 Related Articles

Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).

CD28 Related Gene Family

Immunoglobulins