CD28 involved in several pathways and played different roles in them. We selected most pathways CD28 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
CD28 has several biochemical functions, for example, SH3/SH2 adaptor activity, coreceptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD28 itself. We selected most functions CD28 had, and list some proteins which have the same functions with CD28. You can find most of the proteins on our site.
CD28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD28 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD28.
PIK3R1; GRAP2; CD80; PIK3R1; Pik3r1; GRB2; PRKCQ
Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
Can CD28 protein be used for personalized medicine?
01/13/2023
CD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.
What are the potential clinical applications of targeting CD28 protein?
05/18/2021
Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.
How does CD28 protein impact regulatory T cells (Tregs)?
06/21/2019
CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.
How does CD28 protein impact cancer immunotherapy?
11/26/2018
CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.
Are there any approved therapies targeting CD28 protein?
05/27/2017
Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.
Its unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.
08/24/2021
Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.
08/06/2021
the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.