fgf1
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  • Official Full Name
  • fibroblast growth factor 1 (acidic)
  • Background
  • Fibroblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.
  • Synonyms
  • FGF1; Fibroblast Growth Factor-acidic; FGF-acidic; Basic fibroblast growth factor; BFGF; FGF 2; FGF B; FGF2; FGF2 basic; FGF2_HUMAN; FGFB; Fibroblast growth factor 2 (basic); HBGF 2; HBGF-2; HBGF2; HBGH 2; HBGH2; Heparin binding growth factor 2 precursor; Heparin-binding growth factor 2; Prostatropin
Cat.#:FGF1-322HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF1 Protein (Phe16-Asp155), Met
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Cat.#:FGF1-4094HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FGF1 Protein, GST-tagged
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Cat.#:Fgf1-4096RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fgf1 Protein
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Cat.#:FGF1-564HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 1 (acidic)
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Cat.#:Fgf1-565MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fibroblast Growth Factor 1
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Cat.#:FGF1-09HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor-acidic
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Cat.#:FGF1-12861HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF1, GST-tagged
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Cat.#:FGF1-173HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 1 (acidic, Sf9 Insect Cells Derived)
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Cat.#:FGF1-199HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Acidic Fibroblast Growth Factor, His-tagged
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Cat.#:FGF1-244HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human FGF1, StrepII-tagged
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Cat.#:FGF1-255HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF1 protein
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Cat.#:FGF1-26204THTag:His
Source (Host):Species:Human
Product nameRecombinant Human FGF1, His-tagged
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Cat.#:FGF1-26555THTag:His
Source (Host):Species:Human
Product nameRecombinant Human FGF1, His-tagged
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Cat.#:FGF1-2HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human FGF-1, Acidic
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Cat.#:FGF1-4HTag:N/A
Source (Host):YeastSpecies:Human
Product nameRecombinant Human Acidic Fibroblast Growth Factor
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Cat.#:FGF1-547HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF1 protein, His & GST-tagged
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Cat.#:FGF1-619HTag:Met
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF1, Met-tagged
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Cat.#:FGF1-8498HTag:His
Source (Host):Sf 21 Insect cellsSpecies:Human
Product nameRecombinant Human FGF1, His-tagged
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Cat.#:Fgf1-10MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fibroblast Growth Factor-acidic
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Cat.#:Fgf1-496MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf1, His-tagged
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Cat.#:Fgf1-558MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf1
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Cat.#:Fgf1-572MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf1, None tagged
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Cat.#:FGF1-5837MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FGF1 Protein
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Cat.#:Fgf1-634MTag:Met
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf1
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Cat.#:FGF1-2323RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FGF1 Protein
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Cat.#:Fgf1-257RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fgf1 protein
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Cat.#:Fgf1-631RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fgf1 protein, His & GST-tagged
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Cat.#:FGF1-65CTag:
Source (Host):E. coliSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FGF1
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Cat.#:FGF1-1692RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FGF1 Protein, His-tagged
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Cat.#:FGF1-159CTag:
Source (Host):E. coliSpecies:Canine
Product nameRecombinant Canine FGF1
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Cat.#:FGF1-6735CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FGF1
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Cat.#:FGF1-629STag:His/T7
Source (Host):E. coliSpecies:Sheep
Product nameRecombinant Sheep FGF1 protein, His & T7-tagged
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Cat.#:FGF1-630PTag:His/GST
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig FGF1 protein, His & GST-tagged
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Cat.#:FGF1-021ETag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF1 (16-155aa), Met tagged
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Cat.#:FGF1-013OTag:N/A
Source (Host):RiceSpecies:Human
Product nameRecombinant Human FGF1
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Cat.#:FGF1-26203THTag:
Source (Host):E. coliSpecies:Human
Product nameNative Human FGF1
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Cat.#:FGF1-33BTag:
Source (Host):Species:Bovine
Product nameNative Bovine FGF1
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Cat.#:FGF1-6252HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FGF1 293 Cell Lysate
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Cat.#:FGF1-4344HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human FGF1 protein
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Involved Pathway

FGF1 involved in several pathways and played different roles in them. We selected most pathways FGF1 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
MAPKAPK2A; MAP4K4; BRAF; RPS6KA5; PRKCBB; BDNF; NGF; NRAS; Fgf15; NFKB2
Ras signaling pathway
PLD1; INS; FGF18; PLA2G6; PIK3CB; NF1; RALBP1; NGF; ETS1; SHC3
Rap signaling pathway
VAV2; VEGFB; FGF17; MAP2K6; ACTB; AKT1; MAPK11; KLK1B4; FGF6; INS
PIK-Akt signaling pathway
FGF18; FGF11; FGF20; CD19; ITGB5; INSR; PKN3; ITGA2B; COL6A5; STK11
Hippo signaling pathway
AREG; PRKCI; PPP2R1A; SCRIB; TGFBR2; APC2; LATS1; FZD8; YWHAZ; FZD9
Regulation of actin cytoskeleton
ARHGEF4; FGF5; DIAPH3; GNA13A; PTK2AB; CDC42; RHOAB; PPP1R12A; BAIAP2A; BRAF
Pathways in cancer
GNAS; MSH3; BIRC3; FADD; CTBP2; ITGA2; STAT5B; WNT4; LAMB2; SOS1
Melanoma
FGF5; Fgf15; IGF1R; PDGFRA; MAPK3; HGF; MITF; TRP53; IGF1; NRAS

Protein Function

FGF1 has several biochemical functions, for example, S100 protein binding, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF1 itself. We selected most functions FGF1 had, and list some proteins which have the same functions with FGF1. You can find most of the proteins on our site.
Function
Related Protein
Function S100 protein binding
Related Protein S100B; DDX1; S100A6; S100A11; AGER; S100A1; KCNK3; FGF1; ATP2A2; FGF1A
Function fibroblast growth factor receptor binding
Related Protein FGF10; FRS3; Fgf15; FGF20A; FGF1A; FGF9; FGF20; FGF2; FGF20B; FGF8
Function growth factor activity
Related Protein GDF7; NGF; EGF; TYMP; IGF1; CECR1; LIF; HBEGFB; GPR19; NDR1
Function heparin binding
Related Protein LTF; VEGFAB; MDK; LIPH; CCL2; KAL1; VTN; WISP1A; IMPG2; CTGF
Function protein binding
Related Protein ELK4; MAGEB4; CRELD2; MED17; FAM103A1; CDK5; MINK1; SALL4; MT3; SOCS2

Interacting Protein

FGF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF1.
FGFR1; FGFR2; heparin; intg_av_b3_human; FGFR3; copper(2+); SRPK1; FGFR4; HSPG2

FGF1 Related Articles

Tiede, C; Tang, AAS; et al. Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. PROTEIN ENGINEERING DESIGN & SELECTION 27:145-155(2014).
Aizman, I; Tirumalashetty, BJ; et al. Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators. STEM CELL RESEARCH & THERAPY 5:-(2014).