FGF2 Protein, Fibroblast Growth Factor 2 (basic)

FGF2

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FGF2

Official Full Name Fibroblast Growth Factor 2 (basic)
Background roblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.
Synonyms FGF2; fibroblast growth factor 2 (basic); BFGF; FGFB; HBGF-2; heparin-binding growth factor 2; prostatropin; OTTHUMP00000037513; basic fibroblast growth factor bFGF; Fgf-2
    • Species :
    • Bovine
    • Chicken
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Zebrafish
    • Source :
    • Barley Grain
    • Bovine
    • Bovine brain
    • Bovine Pituitary
    • E.coli
    • HEK293
    • HEK293T
    • Hordeum Vulgare
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mouse
    • Oryza Sativa
    • Sf21 Insect Cell
    • Wheat Germ
    • yeast
    • Tag :
    • Ala
    • Biotin
    • ERHV
    • His
    • GST
    • S
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF2-022H Recombinant Human FGF2 Protein E.coli N/A
    Human FGF2-13H Recombinant Human FGF2 Protein, non-tagged, Biotinylated E.coli N/A
    Bovine FGF2-40B Native Bovine FGF2 Protein Bovine brain N/A
    Human FGF2-001H Recombinant Human FGF2 Protein, His-tagged E.coli His
    Mouse Fgf2-059M Recombinant Mouse Fgf2 Protein E.coli
    Mouse Fgf2-060M Recombinant Mouse Fgf2 Protein E.coli
    Mouse Fgf2-061M Recombinant Mouse Fgf2 Protein E.coli
    Mouse Fgf2-062M Recombinant Mouse Fgf2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Bovine FGF2-12B Recombinant Bovine FGF2 Protein E.coli N/A
    Human DMABT-H18565 Mouse Anti-FGF2 Monoclonal Antibody Mouse N/A
    Human DMABT-H18566 Mouse Anti-FGF2 Monoclonal Antibody Mouse Biotin
    Human FGF2-014O Recombinant Human FGF2 Oryza Sativa N/A
    Human FGF2-022E Recombinant Human FGF2 (143-288aa), Ala tagged E.coli N/A
    Human FGF2-105H Recombinant Human Basic Fibroblast Growth Factor (rDNA derived) Reference standard E.coli N/A
    Human FGF2-108HG GMP Recombinant Human FGF2 Protein E.coli N/A
    Human FGF2-11H Recombinant Human Fibroblast Growth Factor-basic E.coli N/A
    Human FGF2-12H Recombinant Human FGF2 E.coli N/A
    Human FGF2-169H Recombinant Human FGF2 Insect Cell N/A
    Human FGF2-198H Recombinant Human FGF2 protein, His/S-tagged E.coli His/S
    Human FGF2-19H Recombinant Human FGF2 protein, ERHV-His-tagged Barley Grain ERHV/His
    Human FGF2-1H Recombinant Human FGF basic protein E.coli N/A
    Human FGF2-22H Recombinant Human FGF2 protein, GST-tagged Wheat Germ GST
    Human FGF2-26551TH Native Human FGF2 E.coli N/A
    Human FGF2-27258TH Recombinant Human FGF2, His-tagged His
    Human FGF2-27596TH Recombinant Human FGF2 N/A
    Human FGF2-2784H Recombinant Human FGF2 protein, His-tagged E.coli His
    Human FGF2-293H Recombinant Human FGF2, StrepII-tagged Human Cell Strep II
    Human FGF2-41H Recombinant Human FGF2 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FGF2-4345HG GMP Recombinant Human FGF2 protein E.coli N/A
    Human FGF2-482H Recombinant Human FGF2, None tagged E.coli N/A
    Human FGF2-567H Recombinant Human FGF2 protein E.coli N/A
    Human FGF2-590H Recombinant Human FGF2 protein E.coli
    Human FGF2-5H Recombinant Human Basic Fibroblast Growth Factor yeast N/A
    Human FGF2-638HCL Recombinant Human FGF2 cell lysate Insect Cell N/A
    Human FGF2-678H Recombinant Human Fibroblast Growth Factor 2 (basic) (aa 146) E.coli N/A
    Human FGF2-730H Recombinant Human FGF2, Ala-tagged E.coli Ala
    Human FGF2-8499H Recombinant Human FGF2, His-tagged Sf21 Insect Cell His
    Human FGF2-8856H Recombinant Human Fibroblast Growth Factor 2 (basic) Hordeum Vulgare N/A
    Human FGF2-91H Recombinant Human FGF2,His-tagged Insect Cell HIS
    Mouse Fgf2-12M Recombinant Mouse Fgf2 protein E.coli N/A
    Mouse FGF2-1968M Recombinant Mouse FGF2 Protein E.coli N/A
    Mouse Fgf2-199M Recombinant Mouse Fgf2 protein, His/S-tagged E.coli His/S
    Mouse FGF2-5847M Recombinant Mouse FGF2 Protein Mammalian Cell His
    Mouse Fgf2-664M Recombinant Mouse Fibroblast Growth Factor 2 Mouse N/A
    Mouse Fgf2-680M Recombinant Mouse Fibroblast Growth Factor 2 E.coli N/A
    Mouse Fgf2-829M Recombinant Mouse Fgf2 Protein, His-tagged E.coli His
    Rat FGF2-1967R Recombinant Rat FGF2 Protein E.coli N/A
    Rat Fgf2-200R Recombinant Rat Fgf2 protein, His/S-tagged E.coli His/S
    Rat FGF2-2331R Recombinant Rat FGF2 Protein Mammalian Cell His
    Rat Fgf2-40R Recombinant Rat Fgf2 protein E.coli N/A
    Bovine FGF2-018E Recombinant Bovine FGF2 protein E.coli N/A
    Bovine FGF2-1182B Recombinant Bovine Fibroblast Growth Factor 2 (basic) E.coli N/A
    Bovine FGF2-34B Native Bovine bFGF Bovine Pituitary N/A
    Bovine FGF2-4381B Recombinant Bovine FGF2 Protein Yeast N/A
    Bovine FGF2-650B Recombinant Bovine Fibroblast Growth Factor 2 Bovine N/A
    Rabbit FGF2-2785R Recombinant Rabbit FGF2 protein, His-tagged E.coli His
    Rabbit FGF2-4387R Recombinant Rabbit FGF2 Protein Yeast N/A
    Chicken FGF2-6983C Recombinant Chicken FGF2 Mammalian Cell His
    Zebrafish FGF2-12089Z Recombinant Zebrafish FGF2 Mammalian Cell His
    bFGF-10A Recombinant bFGF agarose fast flow N/A

    FGF2 involved in several pathways and played different roles in them. We selected most pathways FGF2 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway MAP4K3; CACNA1H; FGF4; ARRB2B; NTRK2B; RASA2; FASLG; CACNG2A; MAX; PRKACG
    Ras signaling pathway RASAL2; GNG3; PLA2G12A; AKT1; INS; FGF2; FGF17; LOC608458; SHC2; FASLG
    Rap signaling pathway GRIN1; LPAR3; KLK1B4; PARD3; GNAI1; MAPK1; GNAI3; RASGRP3; KIT; MAP2K3
    PIK-Akt signaling pathway TCL1B; VEGFC; GNB1; PTEN; Ifna11; ITGA10; GNGT1; PPP2R2C; LAMC2; PRL
    Signaling pathways regulating pluripotency of stem cells GRB2; MYF5; PIK3CB; INHBC; FZD7; ID1; FZD1; TBX3; BMPR2; WNT9A
    Regulation of actin cytoskeleton CDC42; FGF18A; ITGAL; FGF2; ACTN4; MAPK6; FGF11A; RAC3B; PIK3R3B; MYLPF
    Pathways in cancer APC; VHL; LAMA2; RAD51; PIAS2; PGF; RALGDS; RAC1; RASSF1; SKP2
    Proteoglycans in cancer CBL; FZD8; MET; PLAU; ROCK2; PIK3CD; WNT5B; ITGB5; WNT6; PDPK1
    Melanoma TRP53; HRAS; FGF17; MDM2; NRAS; FGF18; MITF; CDH1; FGF9; MAPK1

    FGF2 has several biochemical functions, for example, chemoattractant activity, cytokine activity, fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF2 itself. We selected most functions FGF2 had, and list some proteins which have the same functions with FGF2. You can find most of the proteins on our site.

    Function Related Protein
    chemoattractant activity VEGFA; LGALS3; FGF2; FGF7; VEGFC; VEGFB; CXCL12A; FGF10; HGF; CCL15
    cytokine activity KITLG; CMTM2B; CCL6; IFNE; IL17A/F1; WNT1; BMP4; IL15; CMTM8; BMP10
    fibroblast growth factor receptor binding FGF8B; FGF20A; FGF21; FGF22; FGF8; FGF20B; FGF5; FRS2; FGF10; FGF18B
    growth factor activity FGF13A; NENF; NDP; PTN; JAG2; IL3; NTF7; GDF6; Artn; TGFB1A
    heparin binding FMOD; SLIT2; GREM2; SERPINE2; PF4V1; SELP; EPYC; BMP7; CXCL10; MDK
    ligand-dependent nuclear receptor transcription coactivator activity BUD31; MED30; CARM1; PPARG; ATXN7L3; CCAR1; PSMC3IP; PRKCBB; ENY2; THRAP3
    protein binding TJP1; PRDM10; EID1; CD28; MVK; ASGR1; AKIP1; PMP2; AP2B1; MTA2

    FGF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF2.

    FGFR1; FGFR2; FGFBP1; chondroitin sulfate; ssr; DCN; FGFR1; FGFR2; q6dtl8_bovin; ANOS1

    Correa, D; Somoza, RA; et al. Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation. OSTEOARTHRITIS AND CARTILAGE 23:443-453(2015).
    Bohnsack, RN; Warejcka, DJ; et al. Expression of Insulin-Like Growth Factor 2 Receptor in Corneal Keratocytes During Differentiation and in Response to Wound Healing. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:7697-7708(2014).

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