CD274 Protein, CD274 CD274 molecule

CD274

Home / Products / CD274

CD274

Official Full Name CD274 CD274 molecule
Background PD-L1, also known as CD274, B7-H1, is a 40 kD type I transmembrane protein member of B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production.
Synonyms CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296;
    • Species :
    • Canine
    • Cynomolgus
    • Cynomolgus Monkey
    • Cynomolgus/Rhesus macaque
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Yeast
    • Tag :
    • Avi
    • Fc
    • His
    • Biotin
    • DDK
    • GST
    • HIgG1 Fc
    • Flag
    • StrepII
    • T7
    • human
    • IgG1
    • LIgG2b Fc
    • mIgG1
    • MIgG2a Fc
    • mouse IgG2a Fc
    • Mouse
    • IgG2a
    • mutant HIgG1 Fc
    • mutant MIgG2a Fc
    • N/A
    • Strep
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Cynomolgus Monkey CD274-199C Recombinant Human CD274 Protein, His-tagged HEK293 Fc
    Human CD274-593H Recombinant Human CD274 Protein HEK293 N/A
    Human CD274-6778H Recombinant Human CD274 Protein, His&T7-tagged E.coli His/T7
    Human CD274-002HA Recombinant Human CD274 protein, MIgG2a Fc-tagged, APC labeled CHO MIgG2a Fc
    Human CD274-002HP Recombinant Human CD274 protein, MIgG2a Fc-tagged, R-PE labeled CHO MIgG2a Fc
    Human CD274-010HA Recombinant Human CD274 protein, mutant HIgG1 Fc-tagged, APC labeled CHO mutant HIgG1 Fc
    Human CD274-010HP Recombinant Human CD274 protein, mutant HIgG1 Fc-tagged, R-PE labeled CHO mutant HIgG1 Fc
    Human CD274-020HA Recombinant Human CD274 protein, HIgG1 Fc-tagged, APC labeled CHO HIgG1 Fc
    Human CD274-020HP Recombinant Human CD274 protein, HIgG1 Fc-tagged, R-PE labeled CHO HIgG1 Fc
    Canine CD274-1058CA Recombinant Canine CD274 protein, Fc-tagged, APC labeled HEK293 Fc
    Canine CD274-1058CP Recombinant Canine CD274 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Cynomolgus CD274-130CA Recombinant Cynomolgus CD274 protein, Fc-tagged, APC labeled HEK293 Fc
    Cynomolgus CD274-130CP Recombinant Cynomolgus CD274 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Cynomolgus CD274-167CA Recombinant Cynomolgus CD274 protein, Fc-tagged, APC labeled HEK293 Fc
    Cynomolgus CD274-167CP Recombinant Cynomolgus CD274 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Mouse Cd274-1707MA Recombinant Mouse Cd274 protein, Fc-tagged, APC labeled NS0 Fc
    Mouse Cd274-1707MP Recombinant Mouse Cd274 protein, Fc-tagged, R-PE labeled NS0 Fc
    Human CD274-175HA Recombinant Human CD274 protein, Fc-tagged, APC labeled CHO Fc
    Human CD274-175HP Recombinant Human CD274 protein, Fc-tagged, R-PE labeled CHO Fc
    Human CD274-178HA Recombinant Human CD274 protein, Fc-tagged, APC labeled CHO Fc
    Human CD274-178HP Recombinant Human CD274 protein, Fc-tagged, R-PE labeled CHO Fc
    Mouse CD274-188MA Recombinant Mouse CD274 protein, MIgG2a Fc-tagged, APC labeled CHO MIgG2a Fc
    Mouse CD274-188MP Recombinant Mouse CD274 protein, MIgG2a Fc-tagged, R-PE labeled CHO MIgG2a Fc
    Mouse CD274-189MA Recombinant Mouse CD274 protein, mutant MIgG2a Fc-tagged, APC labeled CHO mutant MIgG2a Fc
    Mouse CD274-189MP Recombinant Mouse CD274 protein, mutant MIgG2a Fc-tagged, R-PE labeled CHO mutant MIgG2a Fc
    Cynomolgus Monkey CD274-199CA Recombinant Cynomolgus Monkey CD274 protein, Fc-tagged, APC labeled HEK293 Fc
    Cynomolgus Monkey CD274-199CP Recombinant Cynomolgus Monkey CD274 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Human CD274-2142HA Recombinant Human CD274 protein, Fc-tagged, APC labeled Mammalian Cell Fc
    Human CD274-2142HP Recombinant Human CD274 protein, Fc-tagged, R-PE labeled Mammalian Cell Fc
    Human CD274-2146HA Recombinant Human CD274 protein, mouse IgG1-Fc-tagged, APC labeled HEK293 mIgG1/Fc
    Human CD274-2146HP Recombinant Human CD274 protein, mouse IgG1-Fc-tagged, R-PE labeled HEK293 mIgG1/Fc
    Human CD274-2330HA Recombinant Human CD274 protein, Fc-tagged, APC labeled HEK293 Fc
    Human CD274-2330HP Recombinant Human CD274 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Human CD274-339H Recombinant Human CD274 Protein (Met1-Thr239), HIgG1 Fc-tagged, Biotinylated HEK293 HIgG1 Fc
    Human CD274-358H Recombinant Human CD274 protein, Fc-tagged (HPLC-verified) HEK293 human/IgG1/Fc
    Mouse Cd274-359MA Recombinant Mouse Cd274 protein, mouse IgG2a Fc-tagged, APC labeled HEK293 mouse IgG2a Fc
    Mouse Cd274-359MP Recombinant Mouse Cd274 protein, mouse IgG2a Fc-tagged, R-PE labeled HEK293 mouse IgG2a Fc
    Human CD274-364H Recombinant Human CD274 protein, mouse IgG1 Fc-tagged, low endotoxin (HPLC-verified) HEK293 Mouse/IgG1/Fc
    Human CD274-365H Recombinant Human CD274 Protein, His & Fc & Avi-tagged, Biotinylated HEK293 His/Fc/Avi
    Mouse CD274-366M Recombinant Mouse CD274 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human CD274-379H Recombinant Human CD274 Protein, LIgG2b Fc-tagged, low endotoxin HEK293 LIgG2b Fc
    Rat Cd274-561RA Recombinant Rat Cd274 protein, Fc-tagged, APC labeled HEK293 Fc
    Rat Cd274-561RP Recombinant Rat Cd274 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Mouse Cd274-593MA Recombinant Mouse Cd274 protein, Fc-His-tagged, APC labeled HEK293 Fc/His
    Mouse Cd274-593MP Recombinant Mouse Cd274 protein, Fc-His-tagged, R-PE labeled HEK293 Fc/His
    Mouse CD274-785M Recombinant Mouse CD274 Protein (Met1-Thr238), His-tagged, Biotinylated HEK293 His
    Rabbit CD274-788R Recombinant Rabbit CD274 protein, His-tagged HEK293 His
    Mouse Cd274-821MA Recombinant Mouse Cd274 protein, Fc-tagged, APC labeled HEK293 Fc
    Mouse Cd274-821MP Recombinant Mouse Cd274 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Human CD274-002H Recombinant Human CD274, MIgG2a Fc-tagged CHO Fc
    Human CD274-010H Recombinant Human CD274, HIgG1 Fc-tagged, mutant CHO Fc
    Human CD274-020H Recombinant Human CD274, HIgG1 Fc-tagged CHO Fc
    Human CD274-0763H Recombinant Human CD274 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
    Human CD274-0765H Recombinant Human CD274 Protein, GST-Tagged Wheat Germ GST
    Human CD274-1283H Recombinant Human CD274 protein, Avi & His-tagged, Biotinylated HEK293 Avi/His
    Human CD274-1284H Recombinant Human CD274 protein, Avi & Fc-tagged, Biotinylated HEK293 Avi/Fc
    Human CD274-170H Recombinant Human CD274 Protein, DDK/His-tagged HEK293 DDK/His
    Human CD274-172H Recombinant Human CD274 Protein, DDK-tagged Insect Cell DDK
    Human CD274-173H Recombinant Human CD274 Protein, DDK-tagged Insect Cell DDK
    Human CD274-175H Recombinant Human CD274, Fc-tagged CHO Fc
    Human CD274-178H Recombinant Human CD274 Protein, Fc-tagged CHO Fc
    Human CD274-194H Recombinant Human CD274 protein, Strep-tagged HEK293 Strep
    Human CD274-2142H Recombinant Human CD274 Molecule, Fc Chimera Mammalian Cell Fc
    Human CD274-2145H Recombinant Human CD274 protein, His-tagged (HPLC verified) HEK293 His
    Human CD274-2146H Recombinant Human CD274 protein, mouse IgG1 Fc-tagged, low endotoxin (HPLC-verified) HEK293 Mouse/IgG1/Fc
    Human CD274-2330H Recombinant Human CD274, Fc tagged Human Cell Fc
    Human CD274-256H Recombinant Human CD274, His-tagged, Biotinylated HEK293 His
    Human CD274-27112TH Recombinant Human CD274 Wheat Germ N/A
    Human CD274-2735HCL Recombinant Human CD274 cell lysate Human Cell N/A
    Human CD274-3920H Recombinant Human CD274 protein, DDK-tagged Insect Cell DDK
    Human CD274-592H Recombinant Human CD274, His tagged Human Cell His
    Human CD274-6775H Recombinant Human CD274 Molecule, His-tagged E.coli His
    Human CD274-785H Recombinant Human CD274 protein, His-tagged, biotinylated HEK293 His
    Human CD274-8229H Recombinant Human CD274, Biotin-His-tagged HEK293 Biotin/His
    Human CD274-8230H Recombinant Human CD274 protein, His/Fc-tagged, Biotinylated HEK293 His/Fc
    Human CD274-8315H Recombinant Human CD274 NS0 N/A
    Mouse CD274-1285M Recombinant Mouse CD274 protein, Avi & Fc-tagged, Biotinylated HEK293 Avi/Fc
    Mouse Cd274-1707M Recombinant Mouse CD274 Antigen, Fc-tagged NS0 Fc
    Mouse CD274-188M Recombinant Mouse CD274, MIgG2a Fc-tagged CHO Fc
    Mouse CD274-189M Recombinant Mouse Interleukin CD274, MIgG2a Fc-tagged, mutant CHO Fc
    Mouse Cd274-2275M Recombinant Mouse Cd274 protein, His-tagged HEK293 His
    Mouse CD274-2642MCL Recombinant Mouse CD274 cell lysate Human Cell N/A
    Mouse Cd274-359M Recombinant Mouse Cd274 protein, Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Mouse Cd274-593M Recombinant Mouse Cd274, Fc-His tagged Human Cell Fc/His
    Mouse Cd274-6957M Recombinant Mouse CD274 Antigen, His-tagged E.coli His
    Mouse Cd274-721M Recombinant Mouse Cd274, Fc-tagged, Biotinylated Human Cell Fc
    Mouse Cd274-7691M Recombinant Mouse Cd274 protein, His & T7-tagged E.coli His/T7
    Mouse Cd274-821M Recombinant Mouse Cd274 Protein, Fc-tagged HEK293 Fc
    Rat CD274-002RCL Recombinant Rat CD274 cell lysate Human Cell N/A
    Rat Cd274-561R Recombinant Rat Cd274, Fc-tagged Human Cell Fc
    Rat Cd274-562R Recombinant Rat Cd274, His-tagged Human Cell His
    Rat Cd274-7693R Recombinant Rat Cd274 protein, His & GST-tagged E.coli His/GST
    Cynomolgus Monkey CD274-130C Recombinant Cynomolgus CD274, Fc tagged Human Cell N/A
    Cynomolgus Monkey CD274-131C Recombinant Cynomolgus CD274, His tagged Human Cell Fc
    Cynomolgus/Rhesus macaque CD274-167C Recombinant Cynomolgus/Rhesus macaque CD274 protein, Fc-tagged HEK293 human/IgG1/Fc
    Cynomolgus/Rhesus macaque CD274-168C Recombinant Cynomolgus/Rhesus macaque CD274 protein, His-tagged HEK293 His
    Cynomolgus Monkey CD274-914CCL Recombinant Cynomolgus CD274 cell lysate Human Cell N/A
    Rhesus Macaque CD274-732R Recombinant Rhesus monkey CD274 Protein, His-tagged Mammalian Cell His
    Canine CD274-1058C Recombinant Canine CD274 Protein, Fc-tagged HEK293 Fc
    Canine CD274-4380C Recombinant Canine CD274 Protein Yeast N/A
    Rabbit CD274-4367R Recombinant Rabbit CD274 Protein Yeast N/A

    CD274 involved in several pathways and played different roles in them. We selected most pathways CD274 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CD274 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) ESAM; PTPRC; CD226; HLA-F; ICOS; PDCD1LG2; NEO1A; CLDN15LA; CADM3; CLDNH

    CD274 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD274 itself. We selected most functions CD274 had, and list some proteins which have the same functions with CD274. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PRSS8; HRG; PHIP; VGLL2; CSF2; HES1; ZNHIT6; CAMKK1; TCEANC; TMEM51

    CD274 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD274 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD274.

    CD80; PDCD1

    Markwick, LJL; Riva, A; et al. Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients With Acute Alcoholic Hepatitis. GASTROENTEROLOGY 148:590-+(2015).
    Ritprajak, P; Azuma, M; et al. Intrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinoma. ORAL ONCOLOGY 51:221-228(2015).

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy