il3
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  • Official Full Name
  • interleukin 3
  • Background
  • The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
  • Synonyms
  • Colony stimulating factor multiple; Hematopoietic growth factor; IL 3; IL-3; IL3; IL3_HUMAN; Interleukin 3 (colony stimulating factor, multiple); Interleukin 3; Interleukin-3; Mast cell growth factor; MCGF; MGC79398; MGC79399; Multi CSF; Multilineage colony stimulating factor; Multipotential colony stimulating factor; Multipotential colony-stimulating factor; OTTHUMP00000065963; P cell stimulating factor; P-cell-stimulating factor; BPA; PSF; HCGF; Csfmu; nterleukin-3; TTMUSP00000005831; ast cell growth factor
Cat.#:IL3-455MTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IL3 Protein
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Cat.#:Il3-1922HTag:
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human Il3 Protein
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Cat.#:IL3-5192HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human IL3 Protein, GST-tagged
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Cat.#:IL3-4369BTag:
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine IL3 Protein
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Cat.#:IL3-362DTag:N/A
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog Interleukin 3 (colony-stimulating factor, multiple)
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Cat.#:CSF3&IL3-5HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GM-CSF/IL-3 (PIXY321) Fusion Protein
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Cat.#:IL3-145HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human IL3 Active, His-tagged
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Cat.#:IL3-1556HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant human IL3, Active, His-tagged
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Cat.#:IL3-200HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL3
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Cat.#:IL3-378HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IL3, His tagged
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Cat.#:IL3-435HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL3 Protein, His-tagged
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Cat.#:IL3-436HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL3 Protein
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Cat.#:IL3-503HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL3
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Cat.#:IL3-639HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL3 protein, His & GST-tagged
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Cat.#:IL3-8862HTag:
Source (Host):Hordeum vulgareSpecies:Human
Product nameRecombinant Human IL3, His-tagged
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Cat.#:Il3-09MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin-3
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Cat.#:Il3-366MTag:His
Source (Host):Insect cellSpecies:Mouse
Product nameRecombinant Mouse Il3 Protein, His-tagged
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Cat.#:Il3-640MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il3 protein, His & T7-tagged
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Cat.#:Il3-641MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il3 protein, His & GST-tagged
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Cat.#:Il3-644MTag:Met
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il3
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Cat.#:IL3-1093RTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Rat
Product nameRecombinant Rat IL3 Protein, His-tagged
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Cat.#:Il3-576RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il3
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Cat.#:Il3-642RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il3 protein, His & T7-tagged
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Cat.#:Il3-643RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il3 protein, His & GST-tagged
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Cat.#:IL3-2250RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IL3 Protein, His-tagged
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Cat.#:IL3-539RTag:
Source (Host):E. coliSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IL3
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Cat.#:IL3-407DTag:N/A
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog IL3
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Cat.#:IL3-1734CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IL3
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Cat.#:IL3-604HTag:HQ
Source (Host):Hordeum vulgare (barley grain)Species:Human
Product nameRecombinant Human Interleukin 3 (colony-stimulating factor, multiple), HQ-tagged
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Cat.#:Il3-592MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 3
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Cat.#:ll3-542MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Iterleukin 3
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Cat.#:Il3-591RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Interleukin 3
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Cat.#:IL3-08HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin-3
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Cat.#:IL3-120HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Interleukin 3 (Colony-stimulating Factor, Multiple)
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Cat.#:IL3-132HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Interleukin 3 (colony-stimulating factor, multiple), His-tagged
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Cat.#:IL3-275HTag:N/A
Source (Host):S. cerevisiaeSpecies:Human
Product nameRecombinant Human Interleukin 3 (Colony-Stimulating Factor, Multiple)
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Cat.#:IL3-56HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL3, His-tagged
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Cat.#:IL3-88HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GMCSF/IL-3 Fusion Protein
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Cat.#:IL3-607HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IL3 cell lysate
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Cat.#:IL3-445RCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Rat
Product nameRecombinant Rat IL3 cell lysate
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Cat.#:IL3-132HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human IL3 Protein
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Cat.#:IL3-106HTag:
Source (Host):Species:Human
Product nameHuman Interleukin-3 (rDNA derived) Reference standard
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Cat.#:Il3-114MTag:
Source (Host):Species:Mouse
Product nameMouse Interleukin-3 (rDNA derived) Reference standard
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Involved Pathway

IL3 involved in several pathways and played different roles in them. We selected most pathways IL3 participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CCL22; CCR10; Kitl; INHBC; BMP7B; TNFRSF19; IL6; IL17RB; CCL25B; TSLP
PIK-Akt signaling pathway
PIK3R5; FGFR2; PDGFRB; EPOR; HSP90AA1; IL3RA; IKBKG; AKT2; IFNA14; CCNE1
Apoptosis
PIK3R3B; PPP3CCA; PIK3CD; NFKBIA; BNIP3L; IRAK3; BMX; TRAF2; DCC; TP53
Jak-STAT signaling pathway
IL21; IFNW1; STAT1B; IFNG1-2; RAF1A; SOCS1; GRB2B; CCND1; OSM; IL23
Hematopoietic cell lineage
CD36; CSF1; Flt3l; MME; CD9; ITGAM; GP1BB; CD1D2; CD22; CD1B
Fc epsilon RI signaling pathway
PIK3CG; GAB2; MAP2K7; MAP2K1; MAPK11; VAV1; IL13; IL5; PIK3CA; SOS1
Transcriptional misregulation in cancer
TRP53; NGFR; TLX1; SLC45A3; MLF1; HOXA9; JMJD1C; IL3; KDM6A; NCOR1
Asthma
MS4A2; IL13; EPX; HLA-DRB3; HLA-DPA1; FCER1G; IL4; IL9; H2-AB1; HLA-DMA

Protein Function

IL3 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-3 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL3 itself. We selected most functions IL3 had, and list some proteins which have the same functions with IL3. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein CSF1A; CCL38A.5; IL1F10; BMP10; THPO; TNFRSF11B; BMP5; TNFSF14; IL22; CSF1B
Function growth factor activity
Related Protein EFEMP1; DKK1; FGF12; GPI; CSPG5; COL20A1; INHA; IL11; FGF1A; JAG2
Function interleukin-3 receptor binding
Related Protein RNF41; IL3

Interacting Protein

IL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL3.
CSF2RB

IL3 Related Articles

Barr, TP; Kornberg, D; et al. Validation of endothelin B receptor antibodies reveals two distinct receptor-related bands on Western blot. ANALYTICAL BIOCHEMISTRY 468:28-33(2015).
Abrishami, M; Pastushok, L; et al. Synthetic Anti-IL3 Receptor Antibodies As Therapeutics to Block Innate Imatinib Resistance in Chronic Myelogenous Leukemia. BLOOD 124:-(2014).

IL3 Related Gene Family

IL Cytokines