Recombinant Human Interleukin 28B (interferon, lambda 3)
| Cat.No. : | IL28B-600H |
| Product Overview : | Recombinant human IL28Bis expressed in human 293 cells with an apparent molecular mass of 24 kDa.This cytokine is produced in a serum-free, chemically defined media.Production in human 293 cells offers authentic human post-translationalmodification which contributes to stability in cell growth media and otherapplications. The purity is greater than 95%. |
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- Gene Information
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| Cat. No. : | IL28B-600H |
| Description : | IL28 is a cytokinethat comes in two isoforms, IL28A and IL28B, and plays a role in immunedefense against viruses, including the induction an antiviral state byturning on Mx proteins, 2",5"-oligoadenylate synthetase as well as ISGF3G(Interferon Stimulated Gene Factor 3). IL28A and IL28B belong to the type IIIinterferon family of cytokines and are highly similar (in amino acidsequence) to IL-29. |
| Source : | HEK 293 cells |
| Species : | Human |
| Purity : | >95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel was stainedwith Coomassie blue. |
| Molecular Mass : | 24 kDa monomer,non-glycosylated. |
| Endotoxin Level : | Endotoxin Free <1EU/μg |
| Biological Activity : | 0.1 to 1 ng/mL ED50 |
| Specific Activity : | The specificactivity was determined by the dose dependent protection of the cytopathiceffect on A549 cells (human lung adenocarcinoma epithelial cell line) thatwere challenged with encephalomyocarditis (EMC) virus. |
| OfficialSymbol : | IL28B |
| Pathways : | Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway |
| Gene Name : | IL28B interleukin 28B(interferon, lambda 3) [ Homo sapiens ] |
| Synonyms : | IL28B;interleukin 28B (interferon, lambda 3); IFNL3; IL28C; IL-28B; interleukin-28B;IL-28C; IFN-lambda-3; IFN-lambda-4; interleukin 28C; interleukin-28C;cytokine Zcyto22; interferon lambda-3; interferon lambda-4; interferon,lambda 3; interferon, lambda 4; Interleukin-28B; Interferon lambda-4; Cytokine Zcyto22; Interferon lambda-3; Interleukin-28C |
| Gene ID : | 282617 |
| mRNA Refseq : | NM_172139 |
| Protein Refseq : | NP_742151 |
| MIM : | 607402 |
| UniProt ID : | Q8IZI9 |
| Chromosome Location : | 19q13.13 |
| Function : | cytokine activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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