||RecombinantRat Il3 produced in E. coli is asingle, non-glycosylated polypeptide chain containing 144 amino acids andhaving a molecular mass of 16.3 kD.
||Il3 is apleiotropic cytokine and member of the Il3 family, predominantly expressed byactivated T cells, which stimulates the differentiation and proliferation ofhaematopoietic stem cells into myeloid progenitor cells, and theproliferation of mast cells, macrophages, granulocytes and erythrocytes.
||Purifiedrecombinant protein – lyophilized.
||Recombinant Il3 expressedin E. coli.
||16.3 kD (144 aminoacid residues)
||> 98% by SDS-PAGEand HPLC analysis.
||Prior toreconstitution store at +4°C. Store at ±20°C. Storage in frost-free freezersis not recommended. This product should be stored undiluted. Avoid repeatedfreezing and thawing as this may denature the antibody. Should this productcontain a precipitate we recommend microcentrifugation before use.
|Pathways||Apoptosis; Asthma;Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway;Hematopoietic cell lineage; Jak-STAT signaling pathway|