"IL22RA1" Related Products

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Recombinant Human IL22RA1, MIgG2a Fc-tagged

Cat.No.: IL22RA1-781H
Product Overview: The extracellular domain of human IL-22RA1 (AAH29273.1)(Pro18-Thr228) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description: The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be areceptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein andinterleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10(IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in thechromosomal region 1p36.
Source: CHO cell
Species: Human
Tag: MIgG2a Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells.
Molecular Mass: 50KDa (monomer)
AA Sequence: Pro18-Thr228
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: IL22RA1 interleukin 22 receptor, alpha 1 [ Homo sapiens ]
Official Symbol: IL22RA1
Synonyms: IL22RA1; interleukin 22 receptor, alpha 1; IL22R, interleukin 22 receptor; interleukin-22 receptor subunit alpha-1; CRF2 9; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9; IL22R; CRF2-9; IL22R1;
Gene ID: 58985
mRNA Refseq: NM_021258
Protein Refseq: NP_067081
MIM: 605457
UniProt ID: Q8N6P7
Chromosome Location: 1p36.11
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function: interferon receptor activity; receptor activity;

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