"IL4" Related Products

Recombinant Human IL4, His-tagged

Cat.No.: IL4-29002TH
Product Overview: Recombinant full length (mature) protein, corresponding to amino acids 25-153 of Human IL4, with an amino-terminal hexahistidine tag.
Description: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Conjugation: HIS
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the IL-4/IL-13 family.
Gene Name: IL4 interleukin 4 [ Homo sapiens ]
Official Symbol: IL4
Synonyms: IL4; interleukin 4; interleukin-4; B cell growth factor 1; B_cell stimulatory factor 1; BCGF 1; BCGF1; BSF1; IL 4; lymphocyte stimulatory factor 1; MGC79402;
Gene ID: 3565
mRNA Refseq: NM_000589
Protein Refseq: NP_000580
MIM: 147780
Uniprot ID: P05112
Chromosome Location: 5q23-q31
Pathway: Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem;
Function: cytokine activity; growth factor activity; interleukin-4 receptor binding; protein binding;

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