Active Recombinant Human IL6
| Cat.No. : | IL6-1H |
| Product Overview : | Human Interleukin-6 (RECOMBINANT) is produced in genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant viruses, and purified by sequential chromatography. |
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| Description : | Human Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 amino acid residues, and has a 42% homology with murine IL-6. |
| Source : | Sf9 cells |
| Species : | Human |
| Form : | Frozen liquid solution (PBS) at 0.50 mg/ml (50 μl/vial) |
| Bio-activity : | 3H-thymidine uptake by B9 murine thymoma cell line that is IL-6 dependent. |
| Molecular Mass : | 20-21 KDa (glycoprotein) |
| Purity : | Over 85% pure by SDS gel electrophoresis. There is< 1ng/mg> |
| Stability : | At least 1 year at -80°C. |
| Storage : | Store at -80°C. |
| Gene Name : | IL6 interleukin 6 [ Homo sapiens (human) ] |
| Official Symbol : | IL6 |
| Synonyms : | HGF; BSF2; HSF; IFNB2; IL-6; CDF; BSF-2; B-cell stimulatory factor 2; CTL differentiation factor; Hybridoma growth factor; Interferon beta-2; Interleukin-6 precursor; interleukin 6 (interferon, beta 2); IL6 |
| Gene ID : | 3569 |
| mRNA Refseq : | NM_000600 |
| Protein Refseq : | NP_000591 |
| MIM : | 147620 |
| UniProt ID : | P05231 |
| Chromosome Location : | 7p21 |
| Pathway : | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Prion disease, Toll-like receptor signaling pathway |
| Function : | Cytokine activity, Interleukin-6 receptor binding, Protein binding |
Products Types
| ◆ Recombinant Protein | ||
| IL6-093I | Active Recombinant Human IL6 Protein (184 aa) | +Inquiry |
| IL6-516H | Recombinant Human IL6 Protein | +Inquiry |
| IL6-208H | Recombinant Active Human IL6 Protein, His-tagged(C-ter) | +Inquiry |
| Il6-116M | Recombinant Mouse Il6 Protein, MYC/DDK-tagged | +Inquiry |
| IL6-4394A | Recombinant Atlantic Salmon IL6 Protein | +Inquiry |
| ◆ Lysates | ||
| IL6-5224HCL | Recombinant Human IL6 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.
The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.
Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.
Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.
This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.
The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.
Customer Reviews (3)
Write a reviewAccurate localization and function within the cell.
The binding affinity and affinity constant with the target are high.
Can form a stable micellar structure.
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