"Il15" Related Products

Expand
Expand

Recombinant Mouse Interleukin 15, His-tagged

Cat. No.: Il15-533M
Product Overview: Recombinant Mouse IL-15 was expressed in E. coli and purified by using conventional chromatography after refolding of the isolated inclusion bodies in a redox buffer.
Description: Interleukin (IL)-15 is a pleiotropic cytokine that plays a pivotal role in both innate and adaptive immunity and has structural similarity to IL-2 that is secreted by mononuclear phagocytes following infection by viruses. Stimulation by IL-15 requires interaction of Il-15 with components of IL-2R, including IL-2Rbeta and probably IL-2R gamma, but not IL-2R alpha. This cytokine is produced by a wide variety of cells and tissues and like IL-2, stimulates the proliferation of T-lymphocytes and induces the generation of cytotoxic T-lymphocytes (CTLs) and lymphokine-activated killer (LAK) cells.
Concentration: 0.5 mg/ml
Source: Mouse
Host: E.coli
Form: Supplied as a liquid in PBS, pH7.4, containing 10% glycerol.
Purity: > 90% by SDS - PAGE
Sequence: 49-162 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMNW IDVRYDLEKI ESLIQSIHID TTLYTDSDFH PSCKVTAMNC FLLELQVILH EYSNMTLNET VRNVLYLANS TLSSNKNVAE SGCKECEELE EKTFTEFLQS FIRIVQMFIN TS
Molecular Mass: 17.6 kDa (152aa), confirmed by MALDI-TOF.
Applications: SDS-PAGE
Endotoxin Levels: < 1.0 EU per ug of protein (determined by LAL method)
Bioactivity: Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 1 ng/ml.
Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: Il15 interleukin 15 [ Mus musculus ]
Official Symbol: Il15
Synonyms: Il15; interleukin 15; AI503618
Gene ID: 16168
mRNA Refseq: NM_008357
Protein Refseq: NP_032383
UniProt ID: P48346
Chromosome Location: 8 C2; 8 38.0 cM
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function: cytokine activity; cytokine receptor binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.