"IL21" Related Products

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Recombinant Human IL21, StrepII-tagged

Cat.No.: IL21-292H
Product Overview: Purified, full-length human recombinant IL21 protein (amino acids 23-155, 133 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 15.5 kDa. (Accession NP_001193935; UniProt Q9HBE4)
Description: IL21 is a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.
Source: Human Cells
Species: Human
Tag: StrepII
Form: Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free)
Protein length: 23-155, 133 a.a.
AA Sequence: QGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLK RKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
Endotoxin: <0.1 eu per μg protein by lal
Purity: 90% by SDS-PAGE
Storage: 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for up to 1 month.
Gene Name: IL21 interleukin 21 [ Homo sapiens ]
Official Symbol: IL21
Synonyms: IL21; interleukin 21; interleukin-21; IL 21; Za11; interleukin-21 isoform; IL-21;
Gene ID: 59067
mRNA Refseq: NM_001207006
Protein Refseq: NP_001193935
MIM: 605384
UniProt ID: Q9HBE4
Chromosome Location: 4q26-q27
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function: cytokine activity; cytokine receptor binding; interleukin-2 receptor binding;

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