"IL28A" Related Products

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Recombinant Human IL28A, MIgG2a Fc-tagged

Cat.No.: IL28A-311H
Product Overview: The extracellular domain of human IL-28A (AAI13582.1) (Val26-Val200) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA)
Source: CHO cell
Species: Human
Tag: MIgG2a Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured in an anti-viral assay.
Molecular Mass: 46KDa (monomer)
AA Sequence: Val26-Val200
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ]
Official Symbol: IL28A
Synonyms: IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon lambda-2; interferon-lambda 2; IL-28A;
Gene ID: 282616
mRNA Refseq: NM_172138
Protein Refseq: NP_742150
MIM: 607401
UniProt ID: Q8IZJ0
Chromosome Location: 19q13.13
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function: cytokine activity;

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