Active Recombinant Rat Il7

• Cat.No.: Il7-670R
• Product Overview: Recombinant Rat Il7 (Accession # NP_037242) Asp26-Ile154, fused with an N-terminal Met, was produced in E. coli.

Specification

• Source: E. coli
• Species: Rat
• Predicted N Terminal: Starts at Met
• Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). Yokota, T. et al. (1986) Proc. Natl. Acad. Sci. USA 83:5894. The ED50 for this effect is typically 0.1-0.6 ng/mL.
• Molecular Mass: Recombinant Rat Il7, Met-tagged has a calculated MW of 15 kDa. In SDS-PAGE migrates as 15 kDa, reducing conditions.
• Protein length: Asp26-Ile154
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Il7 interleukin 7 [ Rattus norvegicus ]
• Official Symbol: Il7
• Synonyms: IL7; interleukin 7; interleukin-7; IL-7
• Gene ID: 25647
• mRNA Refseq: NM_013110
• Protein Refseq: NP_037242

Reviews

03/27/2022

Effective in signal transduction pathway.

04/17/2021

IL7 has good absorbability and high bioavailability.

11/27/2020

Good stability under different environmental conditions

Q&As

What are the application scenarios of IL7?

IL7 is widely used in the research and development of immunotherapy protocols, can enhance the body's immune function, for the treatment of cancer, infection, autoimmune diseases and other diseases.

What is the mechanism of IL7 in the treatment of bladder cancer?

IL7 can activate the body's immune system and enhance the immune cells' attack on bladder cancer.

What is the optimal dose of IL7 in the treatment of leukemia?

The dosage of IL7 in the treatment of leukemia needs to be calculated individually according to the specific situation of the patient.

Does the efficacy of IL7 in the treatment of infectious diseases?

It can enhance the function of the body's immune system, and has a certain effect on some infectious diseases.

Are there have any efficacy of IL7 in the treatment of specific cancers?

Recombinant IL7 protein may have some therapeutic effect on specific cancers by activating T cells, but further clinical studies are needed.

How to prepare IL7?

This is obtained by recombinant DNA technology, inserting foreign genes into the host expression system, and then through purification and other steps.