pdcd1
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  • Official Full Name
  • Pdcd1 programmed cell death 1
  • Background
  • CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily.
  • Synonyms
  • PDCD1; programmed cell death 1; programmed cell death protein 1; mPD-1; protein PD-1; PD-1; Pdc1; Ly101;
Cat.#:PDCD1-031HATag:MIgG2a Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, MIgG2a Fc-tagged, APC labeled
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Cat.#:PDCD1-031HPTag:MIgG2a Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, MIgG2a Fc-tagged, R-PE labeled
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Cat.#:PDCD1-032HATag:HIgG1 Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, HIgG1 Fc-tagged, APC labeled
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Cat.#:PDCD1-032HPTag:HIgG1 Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, HIgG1 Fc-tagged, R-PE labeled
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Cat.#:PDCD1-034HATag:mutant HIgG1 Fc-tagged
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, mutant HIgG1 Fc-tagged, APC labeled
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Cat.#:PDCD1-034HPTag:mutant HIgG1 Fc-tagged
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, mutant HIgG1 Fc-tagged, R-PE labeled
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Cat.#:PDCD1-1002CTag:His
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus PDCD1 Protein (Met1-Gln167), His-tagged
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Cat.#:PDCD1-1003CTag:AVI-Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus PDCD1 Protein (Met1-Gln167), AVI-Fc-tagged, Biotinylated
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Cat.#:PDCD1-188HATag:Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, APC labeled
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Cat.#:PDCD1-188HPTag:Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, R-PE labeled
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Cat.#:PDCD1-189HATag:Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, APC labeled
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Cat.#:PDCD1-189HPTag:Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, R-PE labeled
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Cat.#:PDCD1-191HATag:Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, APC labeled
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Cat.#:PDCD1-191HPTag:Fc
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, R-PE labeled
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Cat.#:PDCD1-2022HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, His-tagged
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Cat.#:Pdcd1-206MTag:Fc-Avi
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Pdcd1 Protein, Fc-Avi-tagged, Biotinylated
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Cat.#:PDCD1-258HTag:Fc-Avi-His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, Fc-Avi-His-tagged, Biotinylated
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Cat.#:PDCD1-259HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, His-Avi-tagged, Biotinylated
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Cat.#:PDCD1-260HTag:Fc-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, Fc-Avi-tagged, Biotinylated
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Cat.#:PDCD1-3244HATag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 protein, Fc-His-tagged, APC labeled
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Cat.#:PDCD1-3244HPTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 protein, Fc-His-tagged, R-PE labeled
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Cat.#:PDCD1-355HTag:MIgG2a Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, MIgG2a Fc-tagged
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Cat.#:PDCD1-361HTag:LIgG2b Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, LIgG2b Fc-tagged, low endotoxin
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Cat.#:PDCD1-362HTag:Strep
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, Strep-tagged
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Cat.#:PDCD1-369MTag:MIgG2a Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse PDCD1 Protein, MIgG2a Fc-tagged, low endotoxin
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Cat.#:PDCD1-370MTag:Fc/Avi
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse PDCD1 Protein, Fc & Avi-tagged, Biotinylated
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Cat.#:PDCD1-371RTag:His
Source (Host):HEK293Species:Rabbit
Product nameRecombinant Rabbit PDCD1 Protein, His-tagged
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Cat.#:PDCD1-372RTag:Fc
Source (Host):HEK293Species:Rabbit
Product nameRecombinant Rabbit PDCD1 Protein, Fc-tagged
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Cat.#:PDCD1-384HTag:His/Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein (Met1-Gln167), His-Fc-tagged, Biotinylated
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Cat.#:PDCD1-801MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse PDCD1 Protein (Met1-Gln167), His-tagged
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Cat.#:PDCD1-821HATag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, APC labeled
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Cat.#:PDCD1-821HPTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged, R-PE labeled
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Cat.#:PDCD1-625MTag:DDK/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse PDCD1 Protein, DDK/His-tagged
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Cat.#:PDCD1-031HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDCD1, MIgG2a Fc-tagged
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Cat.#:PDCD1-032HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDCD1, HIgG1 Fc-tagged
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Cat.#:PDCD1-034HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDCD1, HIgG1 Fc-tagged, mutant
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Cat.#:PDCD1-1589HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD1, GST-tagged
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Cat.#:PDCD1-172HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1, no tag
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Cat.#:PDCD1-182HTag:DDK/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 Protein, DDK/His-tagged
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Cat.#:PDCD1-188HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDCD1, Fc-tagged
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Cat.#:PDCD1-189HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDCD1, Fc-tagged
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Cat.#:PDCD1-190HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDCD1 Protein, His-tagged
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Cat.#:PDCD1-191HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDCD1 Protein, Fc-tagged
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Cat.#:PDCD1-206HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1, His-tagged, C13&N15 Labeled
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Cat.#:PDCD1-217HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1, His-tagged
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Cat.#:PDCD1-257HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1, His-tagged, Biotinylated
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Cat.#:PDCD1-28HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 protein, His-tagged
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Cat.#:PDCD1-2943HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human PDCD1 protein, GST-tagged
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Cat.#:PDCD1-29487THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PDCD1
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Cat.#:PDCD1-3244HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1, Fc-His tagged
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Cat.#:PDCD1-472HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD1 protein, His-tagged
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Cat.#:PDCD1-821HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 protein, Fc-tagged
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Cat.#:PDCD1-822HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1, His tagged
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Cat.#:PDCD1-839HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD1 protein, His-tagged
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Cat.#:Pdcd1-041MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Pdcd1, MIgG2a Fc-tagged
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Cat.#:Pdcd1-160MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Pdcd1 protein, Fc-tagged
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Cat.#:Pdcd1-205MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Pdcd1, Fc tagged, Biotinylated
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Cat.#:Pdcd1-2303MTag:FC/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Pdcd1, Fc-His tagged
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Cat.#:Pdcd1-823MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Pdcd1, His tagged
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Cat.#:Pdcd1-560RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Pdcd1, Fc-tagged
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Cat.#:Pdcd1-840RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Pdcd1 protein, His & GST-tagged
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Cat.#:Pdcd1-982RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Pdcd1 protein, His-tagged
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Cat.#:PDCD1-1223CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PDCD1 Protein, Fc-tagged
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Cat.#:PDCD1-5223CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PDCD1, His-tagged
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Cat.#:PDCD1-775CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PDCD1 Protein, His-tagged
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Cat.#:PDCD1-1221RTag:Fc
Source (Host):HEK293Species:Rhesus Macaque
Product nameRecombinant Rhesus PDCD1 Protein, Fc-tagged
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Cat.#:PDCD1-1222RTag:His
Source (Host):HEK293Species:Rhesus Macaque
Product nameRecombinant Rhesus PDCD1 Protein, His-tagged
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Cat.#:PDCD1-3338RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PDCD1 Protein, His-tagged
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Cat.#:PDCD1-1057CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine PDCD1 Protein, Fc-tagged
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Cat.#:PDCD1-384CTag:His
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine PDCD1 protein, His-tagged
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Cat.#:PDCD1-2873HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDCD1 cell lysate
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Cat.#:PDCD1-2628MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse PDCD1 cell lysate
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Cat.#:PDCD1-001RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat PDCD1 cell lysate
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Involved Pathway

PDCD1 involved in several pathways and played different roles in them. We selected most pathways PDCD1 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDCD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
ICAM2; ITGAV; BMA2; CNTN1A; MPZL1L; PVRL3; OCLNB; NEGR1; CLDN15A; CLDN4
T cell receptor signaling pathway
NFKBIA; LAT; FOS; AKT2; MAPK13; LCP2; TEC; LCK; MUC1; NFKBIB

Protein Function

PDCD1 has several biochemical functions, for example, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDCD1 itself. We selected most functions PDCD1 had, and list some proteins which have the same functions with PDCD1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein SERTAD1; EVC2; NAP1L2; PPP1R8; STK3; ECSIT; REST; CYLD; SH2D1B; ETS2
Function signal transducer activity
Related Protein SH2B1; UNC13B; GNA13; GNAV1; ZDHHC13; GNA11; PLCB3; GPR15; SLC35B2; GULP1

Interacting Protein

PDCD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDCD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDCD1.
CD274; PTPN6; PTPN11; AGO1

PDCD1 Related Articles

Zamani, MR; Asbagh, FA; et al. Association between a PD-1 gene polymorphism and antisperm antibody-related infertility in Iranian men. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS 32:103-106(2015).
Kenefeck, R; Wang, CJ; et al. Follicular helper T cell signature in type 1 diabetes. JOURNAL OF CLINICAL INVESTIGATION 125:292-303(2015).