GPCRs Class A
🧪 P2ry12-6461M
Source: Mammalian Cells
Species: Mouse
Tag:
Conjugation:
Protein Length: Full Length
🧪 MC1R-3087HFL
Source: Wheat Germ
Species: Human
Tag:
Conjugation:
Protein Length: Full Length
Class A GPCRs are the largest and most varied group, making up about 48% of all GPCR receptors. This class includes receptors for light, like rhodopsin, as well as key neurotransmitter receptors for dopamine and serotonin, and hormone receptors, such as adrenergic receptors. What sets Class A apart is its structure: these receptors have a short N-terminus and a specific Asp-Arg-Tyr (DRY) motif in their third transmembrane segment, which plays a crucial role in activating G-proteins. By focusing on Class A and its essential functions, we support research and innovation in areas spanning vision, mental health, and hormone-related processes.